Clayon B Hamilton1, Monica R Maly2, Jessica M Clark3, Mark Speechley4, Robert J Petrella5, Bert M Chesworth6. 1. Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences ; School of Physical Therapy. 2. School of Physical Therapy ; School of Rehabilitation Science, McMaster University, Hamilton, Ont. 3. Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences. 4. Department of Epidemiology and Biostatistics. 5. Department of Family Medicine, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ont. 6. Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences ; School of Physical Therapy ; Department of Epidemiology and Biostatistics.
Abstract
PURPOSE: To determine whether activity-modifying behaviour mediates the relationship between the severity of knee pain and each of physical function and knee-related quality of life. METHODS: A total of 105 participants with medial knee pain and no diagnosis of knee osteoarthritis (mean age 52.2 [SD 6.7] y) completed two self-report questionnaires. The Questionnaire to Identify Knee Symptoms assessed activity-modifying behaviour; the Knee injury and Osteoarthritis Outcome Score assessed pain severity, physical function, and knee-related quality of life. Simple mediation analysis was performed using linear regression. RESULTS: The unstandardized regression coefficient for activity-modifying behaviour revealed partial mediation of the effect of pain severity on physical function (0.31 (SE 0.09), p<0.001) and on knee-related quality of life (0.24 (SE 0.07), p<0.001). After accounting for activity-modifying behaviour, the variance in physical function that was explained by pain decreased from 45% to 15%, and the variance in knee-related quality of life that was explained by pain decreased from 64% to 25%. CONCLUSION: Activity-modifying behaviour partially mediates the relationship between pain severity and physical function and between pain severity and knee-related quality of life. Activity-modifying behaviour may thus counteract the impact of knee pain on physical function and knee-related quality of life, which explains why it is used by people with emergent knee pain.
PURPOSE: To determine whether activity-modifying behaviour mediates the relationship between the severity of knee pain and each of physical function and knee-related quality of life. METHODS: A total of 105 participants with medial knee pain and no diagnosis of knee osteoarthritis (mean age 52.2 [SD 6.7] y) completed two self-report questionnaires. The Questionnaire to Identify Knee Symptoms assessed activity-modifying behaviour; the Knee injury and Osteoarthritis Outcome Score assessed pain severity, physical function, and knee-related quality of life. Simple mediation analysis was performed using linear regression. RESULTS: The unstandardized regression coefficient for activity-modifying behaviour revealed partial mediation of the effect of pain severity on physical function (0.31 (SE 0.09), p<0.001) and on knee-related quality of life (0.24 (SE 0.07), p<0.001). After accounting for activity-modifying behaviour, the variance in physical function that was explained by pain decreased from 45% to 15%, and the variance in knee-related quality of life that was explained by pain decreased from 64% to 25%. CONCLUSION: Activity-modifying behaviour partially mediates the relationship between pain severity and physical function and between pain severity and knee-related quality of life. Activity-modifying behaviour may thus counteract the impact of knee pain on physical function and knee-related quality of life, which explains why it is used by people with emergent knee pain.
Entities:
Keywords:
activities of daily living; arthralgia; behaviour; knee; quality of life
Authors: Jasmijn F M Holla; Diana C Sanchez-Ramirez; Marike van der Leeden; Johannes C F Ket; Leo D Roorda; Willem F Lems; Martijn P M Steultjens; Joost Dekker Journal: J Behav Med Date: 2014-05-20