Literature DB >> 24381085

Intervening in the psychopath's brain.

Walter Glannon1.   

Abstract

Psychopathy is a disorder involving personality and behavioral features associated with a high rate of violent aggression and recidivism. This paper explores potential psychopharmacological therapies to modulate dysfunctional neural pathways in psychopaths and reduce the incidence of their harmful behavior, as well as the ethical and legal implications of offering these therapies as an alternative to incarceration. It also considers whether forced psychopharmacological intervention in adults and children with psychopathic traits manifesting in violent behavior can be justified. More generally, the paper addresses the question of how to weigh the psychopath's presumptive right to non-interference in his brain and mind against the public interest in avoiding harm.

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Year:  2014        PMID: 24381085     DOI: 10.1007/s11017-013-9275-z

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN: 1386-7415


  18 in total

1.  Neurobiological basis of psychopathy.

Authors:  R James R Blair
Journal:  Br J Psychiatry       Date:  2003-01       Impact factor: 9.319

2.  Mental impairment, moral understanding and criminal responsibility: psychopathy and the purposes of punishment.

Authors:  Cordelia Fine; Jeanette Kennett
Journal:  Int J Law Psychiatry       Date:  2004 Sep-Oct

3.  Psychopathy in childhood: is it a meaningful diagnosis?

Authors:  Michael Rutter
Journal:  Br J Psychiatry       Date:  2012-03       Impact factor: 9.319

4.  Disruption of the right temporoparietal junction with transcranial magnetic stimulation reduces the role of beliefs in moral judgments.

Authors:  Liane Young; Joan Albert Camprodon; Marc Hauser; Alvaro Pascual-Leone; Rebecca Saxe
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-29       Impact factor: 11.205

Review 5.  The neural correlates of moral decision-making in psychopathy.

Authors:  A L Glenn; A Raine; R A Schug
Journal:  Mol Psychiatry       Date:  2009-01       Impact factor: 15.992

6.  The contribution of emotion and cognition to moral sensitivity: a neurodevelopmental study.

Authors:  Jean Decety; Kalina J Michalska; Katherine D Kinzler
Journal:  Cereb Cortex       Date:  2011-05-26       Impact factor: 5.357

7.  Psychopathy and instrumental aggression: Evolutionary, neurobiological, and legal perspectives.

Authors:  Andrea L Glenn; Adrian Raine
Journal:  Int J Law Psychiatry       Date:  2009-05-05

Review 8.  The neurobiology of psychopathic traits in youths.

Authors:  R James R Blair
Journal:  Nat Rev Neurosci       Date:  2013-10-09       Impact factor: 34.870

9.  Scientific and ethical issues related to deep brain stimulation for disorders of mood, behavior, and thought.

Authors:  Peter Rabins; Brian S Appleby; Jason Brandt; Mahlon R DeLong; Laura B Dunn; Loes Gabriëls; Benjamin D Greenberg; Suzanne N Haber; Paul E Holtzheimer; Zoltan Mari; Helen S Mayberg; Evelyn McCann; Sallie P Mink; Steven Rasmussen; Thomas E Schlaepfer; Dorothy E Vawter; Jerrold L Vitek; John Walkup; Debra J H Mathews
Journal:  Arch Gen Psychiatry       Date:  2009-09

10.  Serotonin selectively influences moral judgment and behavior through effects on harm aversion.

Authors:  Molly J Crockett; Luke Clark; Marc D Hauser; Trevor W Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-27       Impact factor: 11.205

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  4 in total

1.  Psychopathy, neurotechnologies, and neuroethics.

Authors:  Fabrice Jotterand
Journal:  Theor Med Bioeth       Date:  2014-02

2.  Peripubertal stress-induced heightened aggression: modulation of the glucocorticoid receptor in the central amygdala and normalization by mifepristone treatment.

Authors:  Aurelie Papilloud; Vandana Veenit; Stamatina Tzanoulinou; Orbicia Riccio; Olivia Zanoletti; Isabelle Guillot de Suduiraut; Jocelyn Grosse; Carmen Sandi
Journal:  Neuropsychopharmacology       Date:  2018-06-04       Impact factor: 7.853

3.  Morality, Risk-Taking and Psychopathic Tendencies: An Empirical Study.

Authors:  Sam Cacace; Joseph Simons-Rudolph; Veljko Dubljević
Journal:  Front Psychol       Date:  2022-03-03

4.  Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency.

Authors:  Alexandre Bacq; Simone Astori; Elias Gebara; Wei Tang; Bianca A Silva; Jose Sanchez-Mut; Jocelyn Grosse; Isabelle Guillot de Suduiraut; Olivia Zanoletti; Catherine Maclachlan; Graham W Knott; Johannes Gräff; Carmen Sandi
Journal:  Mol Psychiatry       Date:  2018-08-08       Impact factor: 15.992

  4 in total

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