Literature DB >> 24379205

Role of OmpA in the multidrug resistance phenotype of Acinetobacter baumannii.

Younes Smani1, Anna Fàbrega, Ignasi Roca, Viviana Sánchez-Encinales, Jordi Vila, Jerónimo Pachón.   

Abstract

Acinetobacter baumannii has emerged as a nosocomial pathogen with an increased prevalence of multidrug-resistant strains. The role of the outer membrane protein A (OmpA) in antimicrobial resistance remains poorly understood. In this report, disruption of the ompA gene led to decreased MICs of chloramphenicol, aztreonam, and nalidixic acid. We have characterized, for the first time, the contribution of OmpA in the antimicrobial resistance phenotype of A. baumannii.

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Year:  2013        PMID： 24379205      PMCID： PMC3957889          DOI： 10.1128/AAC.02101-13

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Substrate-dependent utilization of OprM or OpmH by the Pseudomonas aeruginosa MexJK efflux pump.

Authors:  Rungtip Chuanchuen; Takeshi Murata; Naomasa Gotoh; Herbert P Schweizer
Journal:  Antimicrob Agents Chemother       Date:  2005-05       Impact factor: 5.191

Review 2.  A molecular Swiss army knife: OmpA structure, function and expression.

Authors:  Stephen G J Smith; Vivienne Mahon; Matthew A Lambert; Robert P Fagan
Journal:  FEMS Microbiol Lett       Date:  2007-06-06       Impact factor: 2.742

3.  Diffusion of beta-lactam antibiotics through oligomeric or monomeric porin channels of some gram-negative bacteria.

Authors:  Yeshayahu Nitzan; Einat Bokobza Deutsch; Izabella Pechatnikov
Journal:  Curr Microbiol       Date:  2002-12       Impact factor: 2.188

4.  Outer membrane protein 38 of Acinetobacter baumannii localizes to the mitochondria and induces apoptosis of epithelial cells.

Authors:  Chul Hee Choi; Eun Young Lee; Yoo Chul Lee; Tae In Park; Hwa Jung Kim; Sung Hee Hyun; Soon Ae Kim; Seong-Kyu Lee; Je Chul Lee
Journal:  Cell Microbiol       Date:  2005-08       Impact factor: 3.715

5.  OmpA is the principal nonspecific slow porin of Acinetobacter baumannii.

Authors:  Etsuko Sugawara; Hiroshi Nikaido
Journal:  J Bacteriol       Date:  2012-05-25       Impact factor: 3.490

6.  Analysis and nucleotide sequence of an origin of DNA replication in Acinetobacter calcoaceticus and its use for Escherichia coli shuttle plasmids.

Authors:  M Hunger; R Schmucker; V Kishan; W Hillen
Journal:  Gene       Date:  1990-03-01       Impact factor: 3.688

7.  Acinetobacter baumannii outer membrane protein A targets the nucleus and induces cytotoxicity.

Authors:  Chul Hee Choi; Sung Hee Hyun; Ji Young Lee; Jun Sik Lee; Yong Seok Lee; Soon Ae Kim; Jeong-Pil Chae; Seung Min Yoo; Je Chul Lee
Journal:  Cell Microbiol       Date:  2007-08-30       Impact factor: 3.715

8.  Expression of the RND-type efflux pump AdeABC in Acinetobacter baumannii is regulated by the AdeRS two-component system.

Authors:  Isabelle Marchand; Laurence Damier-Piolle; Patrice Courvalin; Thierry Lambert
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

Review 9.  An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii.

Authors:  Lenie Dijkshoorn; Alexandr Nemec; Harald Seifert
Journal:  Nat Rev Microbiol       Date:  2007-12       Impact factor: 60.633

10.  Antibiotic stress, genetic response and altered permeability of E. coli.

Authors:  Miguel Viveiros; Myrielle Dupont; Liliana Rodrigues; Isabel Couto; Anne Davin-Regli; Marta Martins; Jean-Marie Pagès; Leonard Amaral
Journal:  PLoS One       Date:  2007-04-11       Impact factor: 3.240
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  41 in total

1.  Cloning of ompA gene from Acinetobacter baumannii into the eukaryotic expression vector pBudCE4.1 as DNA vaccine.

Authors:  Hossein Ansari; Abbas Doosti; Mohammad Kargar; Mahdi Bijanzadeh; Mojtaba Jaafarinia
Journal:  Indian J Microbiol       Date:  2018-02-09       Impact factor: 2.461

Review 2.  The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.

Authors:  Xian-Zhi Li; Patrick Plésiat; Hiroshi Nikaido
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

3.  Molecular Analysis and Expression of bap Gene in Biofilm-Forming Multi-Drug-Resistant Acinetobacter baumannii.

Authors:  Omid Azizi; Fereshteh Shahcheraghi; Himen Salimizand; Farzan Modarresi; Mohammad Reza Shakibaie; Shahla Mansouri; Rashid Ramazanzadeh; Farzad Badmasti; Vajihe Nikbin
Journal:  Rep Biochem Mol Biol       Date:  2016-10

4.  Potent β-Lactam Enhancer Activity of Zidebactam and WCK 5153 against Acinetobacter baumannii, Including Carbapenemase-Producing Clinical Isolates.

Authors:  Bartolome Moya; Isabel M Barcelo; Sachin Bhagwat; Mahesh Patel; German Bou; Krisztina M Papp-Wallace; Robert A Bonomo; Antonio Oliver
Journal:  Antimicrob Agents Chemother       Date:  2017-10-24       Impact factor: 5.191

5.  Tigecycline resistance in Acinetobacter baumannii mediated by frameshift mutation in plsC, encoding 1-acyl-sn-glycerol-3-phosphate acyltransferase.

Authors:  X Li; L Liu; J Ji; Q Chen; X Hua; Y Jiang; Y Feng; Y Yu
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-11-19       Impact factor: 3.267

6.  Roles of ompA of Citrobacter werkmanii in bacterial growth, biocide resistance, biofilm formation and swimming motility.

Authors:  Gang Zhou; Ying-Si Wang; Hong Peng; Su-Juan Li; Ting-Li Sun; Peng-Fei Shen; Xiao-Bao Xie; Qing-Shan Shi
Journal:  Appl Microbiol Biotechnol       Date:  2021-03-25       Impact factor: 4.813

Review 7.  Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside.

Authors:  Ming-Feng Lin; Chung-Yu Lan
Journal:  World J Clin Cases       Date:  2014-12-16       Impact factor: 1.337

8.  Interplay between OmpA and RpoN Regulates Flagellar Synthesis in Stenotrophomonas maltophilia.

Authors:  Chun-Hsing Liao; Chia-Lun Chang; Hsin-Hui Huang; Yi-Tsung Lin; Li-Hua Li; Tsuey-Ching Yang
Journal:  Microorganisms       Date:  2021-06-04

9.  Collateral Sensitivity to β-Lactam Drugs in Drug-Resistant Tuberculosis Is Driven by the Transcriptional Wiring of BlaI Operon Genes.

Authors:  A S Trigos; B W Goudey; J Bedő; T C Conway; N G Faux; K L Wyres
Journal:  mSphere       Date:  2021-05-28       Impact factor: 4.389

10.  Phenotypic and Genotypic Characteristics of Biofilm Formation in Clinical Isolates of Acinetobacter baumannii.

Authors:  Zhaoyinqian Li; Zixuan Ding; Yao Liu; Xinrui Jin; Jingling Xie; Tingting Li; Zhangrui Zeng; Zhibin Wang; Jinbo Liu
Journal:  Infect Drug Resist       Date:  2021-07-07       Impact factor: 4.003
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