Literature DB >> 24378887

Radiation exposure in perfusion CT of the brain.

Adrian Ringelstein1, Ursula Lechel, Delia M Fahrendorf, Jens C Altenbernd, Michael Forsting, Marc Schlamann.   

Abstract

OBJECTIVE: This study aimed to show the simulation of the radiation exposure of the brain during perfusion measurements multi-detector-CT.
MATERIAL AND METHODS: The effective dose and different organ doses were measured with thermoluminescent dosimeters in an Alderson-Rando phantom and compared with the data of a simulation program (CT-Expo V1.6) for varying scan protocols with different tube voltages (in kilovolts) and constant parameters for tube current (270 mAs), scan length (28.8 mm), scan time (40 seconds), slice thickness (24 × 1.2 mm), and number of scans (40) for multi-detector-CT perfusion measurements of the brain.
RESULTS: The thermoluminescent dosimeter measurements yielded effective doses of 3.8 mSv (80 kV), 8.6 mSv (100 kV), 14.1 mSv (120 kV), and 22.2 mSv (140 kV). These values were in line with the data from the simulation program CT-Expo V1.6. The organ doses varied between 97 and 556 mGy (brain), 10.7 and 80.9 mGy (eye lens), 9.6 and 46 mGy (bone marrow), 1.2 and 6.7 mGy (thyroid gland), and 4.1 to 22.3 mGy (skin). The maximum local skin dose ranged from 355 mGy (80 kV) to 1855 mGy (140 kV) in the directly exposed part of the skin.
CONCLUSIONS: The radiation exposure during perfusion measurements of the brain is strongly dependent on the tube voltage and can vary widely even if the other exposure parameters remain constant. Maximum organ doses up to 556 mGy (brain) can be measured. Even if we never reached local organ doses that can cause a direct radiation injury, the review of the tube voltages implemented by the vendor is mandatory beside the limitation of the scanned area by clinical examination and the reduction of the number of scans. Simulation programs are a valuable tool for dose measurements.

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Year:  2014        PMID: 24378887     DOI: 10.1097/RCT.0b013e3182a3f9a0

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  4 in total

1.  Image quality, radiation dose and diagnostic accuracy of 70 kVp whole brain volumetric CT perfusion imaging: a preliminary study.

Authors:  Xiao Kun Fang; Qian Qian Ni; U Joseph Schoepf; Chang Sheng Zhou; Guo Zhong Chen; Song Luo; Stephen R Fuller; Carlo N De Cecco; Long Jiang Zhang; Guang Ming Lu
Journal:  Eur Radiol       Date:  2016-02-06       Impact factor: 5.315

2.  Whole-brain adaptive 70-kVp perfusion imaging with variable and extended sampling improves quality and consistency while reducing dose.

Authors:  I Corcuera-Solano; A M McLellan; A H Doshi; P S Pawha; L N Tanenbaum
Journal:  AJNR Am J Neuroradiol       Date:  2014-07-17       Impact factor: 3.825

Review 3.  Mechanical Thrombectomy in Pregnancy: Report of 2 Cases and Review of the Literature.

Authors:  Pervinder Bhogal; Marta Aguilar; Muhammad AlMatter; Ulrich Karck; Hansjörg Bäzner; Hans Henkes
Journal:  Interv Neurol       Date:  2017-01-19

4.  The value of cerebral CT angiography with low tube voltage in detection of intracranial aneurysms.

Authors:  Kun Tang; Rui Li; Jie Lin; Xiangwu Zheng; Ling Wang; Weiwei Yin
Journal:  Biomed Res Int       Date:  2015-02-01       Impact factor: 3.411

  4 in total

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