Literature DB >> 2437881

Palliation for rectal cancer. Resection? Anastomosis?

M R Moran, D A Rothenberger, C J Lahr, J G Buls, S M Goldberg.   

Abstract

There is no agreement regarding the proper management of patients with advanced carcinoma of the rectum. We performed a study to clarify whether palliative resection with or without primary anastomosis is worthwhile and safe. Among 679 patients managed for cancer of the rectum, 125 were considered incurable and underwent palliative procedures. High and low anterior resections were performed in nine and 57 cases, respectively, abdominoperineal resection in 26, Hartmann's procedure in three, simple diverting colostomy in 17, and transanal excision in 13. The overall postoperative mortality rate was 0.8%. Postoperative morbidity was 18% in abdominal operations and none in local excisions. Among patients treated by abdominal resections, only one required subsequent reoperation for colonic obstruction secondary to local recurrence. The median survival was 6.4 months for patients treated by diverting colostomy, 14.8 months for abdominally resected cases, and 14.7 months for transanal excisions. We conclude that palliative resection, often with primary anastomosis or local transanal excision, can be done safely in patients with incurable rectal cancer. We believe this approach improves the quality of the remaining life for these patients.

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Year:  1987        PMID: 2437881     DOI: 10.1001/archsurg.1987.01400180022004

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  10 in total

1.  Interventional management of malignant colorectal obstruction: use of covered and uncovered stents.

Authors:  Jin Soo Choi; Sung Wook Choo; Kwang Bo Park; Sung Wook Shin; So-Young Yoo; Ji Hye Kim; Young Soo Do
Journal:  Korean J Radiol       Date:  2007 Jan-Feb       Impact factor: 3.500

Review 2.  Abdominoperineal resection for adenocarcinoma of the low rectum.

Authors:  D A Rothenberger; W D Wong
Journal:  World J Surg       Date:  1992 May-Jun       Impact factor: 3.352

3.  Endoscopic Nd:YAG laser treatment of rectosigmoid cancer.

Authors:  L A Loizou; D Grigg; P B Boulos; S G Bown
Journal:  Gut       Date:  1990-07       Impact factor: 23.059

Review 4.  Multi-modality treatment of colorectal liver metastases.

Authors:  Guo-Xiang Cai; San-Jun Cai
Journal:  World J Gastroenterol       Date:  2012-01-07       Impact factor: 5.742

5.  Primary Tumor Resection in Patients with Incurable Localized or Metastatic Colorectal Cancer: A Systematic Review and Meta-analysis.

Authors:  Constantinos Simillis; Eliana Kalakouti; Thalia Afxentiou; Christos Kontovounisios; Jason J Smith; David Cunningham; Michel Adamina; Paris P Tekkis
Journal:  World J Surg       Date:  2019-07       Impact factor: 3.352

6.  Survival benefit in patients after palliative resection vs non-resection colon cancer surgery.

Authors:  A Beham; M Rentsch; K Püllmann; L Mantouvalou; H Spatz; H J Schlitt; A Obed
Journal:  World J Gastroenterol       Date:  2006-11-07       Impact factor: 5.742

7.  Determinants of morbidity and survival after elective non-curative resection of stage IV colon and rectal cancer.

Authors:  Axel Kleespies; Kathrin E Füessl; Hendrik Seeliger; Martin E Eichhorn; Mario H Müller; Markus Rentsch; Wolfgang E Thasler; Martin K Angele; Martin E Kreis; Karl-Walter Jauch
Journal:  Int J Colorectal Dis       Date:  2009-06-03       Impact factor: 2.571

Review 8.  Survival and symptomatic benefit from palliative primary tumor resection in patients with metastatic colorectal cancer: a review.

Authors:  Andrew Eisenberger; R Lawrence Whelan; Alfred I Neugut
Journal:  Int J Colorectal Dis       Date:  2008-03-11       Impact factor: 2.571

9.  Non-curative surgery for colorectal cancer: critical appraisal of outcomes.

Authors:  Wai Lun Law; Wai Fun Chan; Yee Man Lee; Kin Wah Chu
Journal:  Int J Colorectal Dis       Date:  2003-11-15       Impact factor: 2.571

10.  Up-front systemic chemotherapy is a feasible option compared to primary tumor resection followed by chemotherapy for colorectal cancer with unresectable synchronous metastases.

Authors:  Hiroaki Niitsu; Takao Hinoi; Manabu Shimomura; Hiroyuki Egi; Minoru Hattori; Yasuyo Ishizaki; Tomohiro Adachi; Yasufumi Saito; Masashi Miguchi; Hiroyuki Sawada; Masatoshi Kochi; Shoichiro Mukai; Hideki Ohdan
Journal:  World J Surg Oncol       Date:  2015-04-24       Impact factor: 2.754

  10 in total

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