| Literature DB >> 24378048 |
B Bachellerie1, S Ruiz2, J-M Conil1, L Crognier1, T Seguin1, B Georges1, O Fourcade1.
Abstract
Dabigatran is a direct thrombin inhibitor indicated for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation. No reversal agent exists, but hemodialysis has been proposed as dabigatran removal method. We report a case of an 80-year-old man presenting hemorrhage with dabigatran overdose caused by obstructive acute renal failure. Before nephrostomy, several hemodialysis sessions were necessary to remove dabigatran probably because of its large volume of distribution.Entities:
Keywords: Acute renal injury; Dabigatran; Hemodialysis; Hémodialyse; Hémorragie; Insuffisance rénale aiguë; Overdose; Surdosage
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Year: 2013 PMID： 24378048 DOI： 10.1016/j.annfar.2013.11.011
Source DB: PubMed Journal: Ann Fr Anesth Reanim ISSN： 0750-7658