Literature DB >> 24377839

Complementary stereochemical outcomes in proline-based self-regenerations of stereocenters.

Brian J Knight1, Erin E Stache, Eric M Ferreira.   

Abstract

Stereoselective alkylations of proline-based amino amides are described, where high levels of either a cis or trans configuration can be attained simply by the choice of the aminal group. Isobutryaldehyde-derived aminals provide the cis configuration, while 1-naphthaldehyde-derived aminals engender the complementary trans configuration.

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Year:  2013        PMID： 24377839     DOI： 10.1021/ol403320d

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  An analysis of the complementary stereoselective alkylations of imidazolidinone derivatives toward α-quaternary proline-based amino amides.

Authors:  Brian J Knight; Erin E Stache; Eric M Ferreira
Journal:  Tetrahedron       Date:  2015-05-09       Impact factor: 2.457

Review 2.  Reactions of Allylmagnesium Reagents with Carbonyl Compounds and Compounds with C═N Double Bonds: Their Diastereoselectivities Generally Cannot Be Analyzed Using the Felkin-Anh and Chelation-Control Models.

Authors:  Nicole D Bartolo; Jacquelyne A Read; Elizabeth M Valentín; K A Woerpel
Journal:  Chem Rev       Date:  2020-01-06       Impact factor: 60.622

3.  Development of Bis-cyclic Imidazolidine-4-one Derivatives as Potent Antibacterial Agents.

Authors:  Minghui Wang; Ruixuan Gao; Mengmeng Zheng; Peng Sang; Chunpu Li; En Zhang; Qi Li; Jianfeng Cai
Journal:  J Med Chem       Date:  2020-09-24       Impact factor: 7.446
  3 in total

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