D Ntelios1, M Kargakis1, T Topalis2, A Drouzas3, E Potolidis1. 1. Department of Internal Medicine, Volos General Hospital, Volos, Greece. 2. Intensive Care Unit, Volos General Hospital, Volos, Greece. 3. Laboratory of Systematic Botany and Phytogeography, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Abstract
BACKGROUND: A variety of organisms produce potent toxins that impact human health through compromising respiratory function. CASE REPORT: We describe a rare case of abrupt respiratory failure afterNicotiana glaucaingestion in a previously healthy sixty years old female patient. She presented complaining for gait instability and malaise after ingestion of cooked leaves of the wild plant and two hours after the onset she developed respiratory failurefor which she was intubated and mechanically ventilated for two days. The patient fully recovered and was discharged from the hospital. CONCLUSION: Anabasine, the plant's main active ingredient, can cause severe systemic intoxication due to its nicotinic receptor agonist action with respiratory muscle paralysis being the main effect.
BACKGROUND: A variety of organisms produce potent toxins that impact human health through compromising respiratory function. CASE REPORT: We describe a rare case of abrupt respiratory failure afterNicotiana glaucaingestion in a previously healthy sixty years old female patient. She presented complaining for gait instability and malaise after ingestion of cooked leaves of the wild plant and two hours after the onset she developed respiratory failurefor which she was intubated and mechanically ventilated for two days. The patient fully recovered and was discharged from the hospital. CONCLUSION:Anabasine, the plant's main active ingredient, can cause severe systemic intoxication due to its nicotinic receptor agonist action with respiratory muscle paralysis being the main effect.
Authors: Stephen T Lee; Kristin Wildeboer; Kip E Panter; William R Kem; Dale R Gardner; Russell J Molyneux; Cheng-Wei Tom Chang; Ferenc Soti; James A Pfister Journal: Neurotoxicol Teratol Date: 2006-02-20 Impact factor: 3.763
Authors: Francisca Valéria Soares de Araújo Pinho; Gustavo Felipe da Silva; Giulianna Echeverria Macedo; Katiane Raquel Muller; Illana Kemmerich Martins; Ana Paula Lausmann Ternes; José Galberto Martins da Costa; Margareth Linde Athayde; Aline Augusti Boligon; Jean Paul Kamdem; Jeferson Luis Franco; Irwin Rose Alencar de Menezes; Thaís Posser Journal: Evid Based Complement Alternat Med Date: 2014-11-10 Impact factor: 2.629