Literature DB >> 24376136

Facile fabrication of polyanhydride/anesthetic nanoparticles with tunable release kinetics.

Bret D Ulery1, Ho-Man Kan, Bryce A Williams, Balaji Narasimhan, Kevin W-H Lo, Lakshmi S Nair, Cato T Laurencin.   

Abstract

This work illustrates a two-step strategy for the fabrication of polymer/drug nanoparticles. Utilizing solvent/non-solvent precipitation and gaseous basification, composite nanoparticles with 0-100% drug loadings are fabricated. Drug release kinetics are dictated by nanoparticle composition allowing future tuning for therapeutic applications.
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  anesthetics; nanoparticles; pain management; polymers

Mesh：

Substances：

Year:  2013        PMID： 24376136      PMCID： PMC4053479          DOI： 10.1002/adhm.201300521

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  36 in total

1.  Nanosphere based oral insulin delivery.

Authors:  G P Carino; J S Jacob; E Mathiowitz
Journal:  J Control Release       Date:  2000-03-01       Impact factor: 9.776

2.  Randomized study of the effect of local anesthetic volume and concentration on the duration of peripheral nerve blockade.

Authors:  Michael J Fredrickson; Amitha Abeysekera; Richard White
Journal:  Reg Anesth Pain Med       Date:  2012 Sep-Oct       Impact factor: 6.288

3.  Intrathecally administered ropivacaine is less neurotoxic than procaine, bupivacaine, and levobupivacaine in a rat spinal model.

Authors:  Tamie Takenami; Guoqin Wang; Yoshihiro Nara; Sayano Fukushima; Saburo Yagishita; Hiromi Hiruma; Tadashi Kawakami; Hirotsugu Okamoto
Journal:  Can J Anaesth       Date:  2012-03-02       Impact factor: 5.063

4.  Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery.

Authors:  Qiaobing Xu; Michinao Hashimoto; Tram T Dang; Todd Hoare; Daniel S Kohane; George M Whitesides; Robert Langer; Daniel G Anderson
Journal:  Small       Date:  2009-07       Impact factor: 13.281

5.  Sustained local anesthetic release from bioerodible polymer matrices: a potential method for prolonged regional anesthesia.

Authors:  D B Masters; C B Berde; S Dutta; T Turek; R Langer
Journal:  Pharm Res       Date:  1993-10       Impact factor: 4.200

6.  Biodegradable polyanhydride devices of cefazolin sodium, bupivacaine, and taxol for local drug delivery: preparation, and kinetics and mechanism of in vitro release.

Authors:  E S Park; M Maniar; J C Shah
Journal:  J Control Release       Date:  1998-03-02       Impact factor: 9.776

7.  An absorbable local anesthetic matrix provides several days of functional sciatic nerve blockade.

Authors:  Chi-Fei Wang; Alimorad G Djalali; Ankur Gandhi; David Knaack; Umberto De Girolami; Gary Strichartz; Peter Gerner
Journal:  Anesth Analg       Date:  2009-03       Impact factor: 5.108

8.  Prolonged duration local anesthesia with minimal toxicity.

Authors:  Hila Epstein-Barash; Iris Shichor; Albert H Kwon; Sherwood Hall; Michael W Lawlor; Robert Langer; Daniel S Kohane
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-13       Impact factor: 11.205

9.  Design of a protective single-dose intranasal nanoparticle-based vaccine platform for respiratory infectious diseases.

Authors:  Bret D Ulery; Devender Kumar; Amanda E Ramer-Tait; Dennis W Metzger; Michael J Wannemuehler; Balaji Narasimhan
Journal:  PLoS One       Date:  2011-03-03       Impact factor: 3.240

10.  The efficacy of 0.75% levobupivacaine versus 0.75% ropivacaine for peribulbar anesthesia in vitreoretinal surgery.

Authors:  Ashraf M Ghali
Journal:  Saudi J Anaesth       Date:  2012-01
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  4 in total

Review 1.  Delivery of small molecules for bone regenerative engineering: preclinical studies and potential clinical applications.

Authors:  Cato T Laurencin; Keshia M Ashe; Nicole Henry; Ho Man Kan; Kevin W-H Lo
Journal:  Drug Discov Today       Date:  2014-02-06       Impact factor: 7.851

Review 2.  Pain management via local anesthetics and responsive hydrogels.

Authors:  Kyle R Bagshaw; Curt L Hanenbaum; Erica J Carbone; Kevin W H Lo; Cato T Laurencin; Joseph Walker; Lakshmi S Nair
Journal:  Ther Deliv       Date:  2015-02

Review 3.  Degradable polymeric vehicles for postoperative pain management.

Authors:  Natasha C Brigham; Ru-Rong Ji; Matthew L Becker
Journal:  Nat Commun       Date:  2021-03-01       Impact factor: 14.919

Review 4.  Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies.

Authors:  Luman Liu; Prakash G Kshirsagar; Shailendra K Gautam; Mansi Gulati; Emad I Wafa; John C Christiansen; Brianna M White; Surya K Mallapragada; Michael J Wannemuehler; Sushil Kumar; Joyce C Solheim; Surinder K Batra; Aliasger K Salem; Balaji Narasimhan; Maneesh Jain
Journal:  Theranostics       Date:  2022-01-01       Impact factor: 11.600
  4 in total

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