| Literature DB >> 24375713 |
Jian Wen1, Li-Li Zhu, Qing-Wei Bi, Zhu-Qing Shen, Xiao-Xiao Li, Xin Li, Zhen Wang, Zili Chen.
Abstract
Hydrogen-bond mediated coupling of 1,2,3-triazoles to indoles and pyrroles results in N2 selective functionalization of the triazole moiety in moderate to excellent yields. The reaction was tolerant of un-, mono- and disubstituted triazoles and was applied to synthesize tryptophan derived fluorescent amino acids.Entities:
Keywords: 1,2,3-triazole; heterocycles; indole-triazole conjugates; iodination mediated reaction; pyrrole-triazole conjugates; regioselectivity
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Year: 2013 PMID： 24375713 DOI： 10.1002/chem.201302761
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236