Literature DB >> 24375054

Proteinuria: abate or applaud abatacept in proteinuric kidney disease?

Jochen Reiser1, Nada Alachkar2.   

Abstract

T-lymphocyte activation antigen CD80 is a B-cell costimulator and podocyte injury marker originally described in lupus nephritis; CD80 blockade with abatacept disappointed in a lupus nephritis trial. A study now suggests abatacept efficacy in focal and segmental glomerulosclerosis. Small patient numbers and concurrent treatment regimens call for more definitive studies regarding this therapeutic strategy.

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Year:  2013        PMID： 24375054     DOI： 10.1038/nrneph.2013.276

Source DB:  PubMed          Journal:  Nat Rev Nephrol        ISSN： 1759-5061            Impact factor:   28.314


  9 in total

1.  Three-year outcomes from BENEFIT-EXT: a phase III study of belatacept versus cyclosporine in recipients of extended criteria donor kidneys.

Authors:  J O Medina Pestana; J M Grinyo; Y Vanrenterghem; T Becker; J M Campistol; S Florman; V D Garcia; N Kamar; P Lang; R C Manfro; P Massari; M D C Rial; M A Schnitzler; S Vitko; T Duan; A Block; M B Harler; A Durrbach
Journal:  Am J Transplant       Date:  2012-02-02       Impact factor: 8.086

2.  Abatacept in B7-1-positive proteinuric kidney disease.

Authors:  Chih-Chuan Yu; Alessia Fornoni; Astrid Weins; Samy Hakroush; Dony Maiguel; Junichiro Sageshima; Linda Chen; Gaetano Ciancio; Mohd Hafeez Faridi; Daniel Behr; Kirk N Campbell; Jer-Ming Chang; Hung-Chun Chen; Jun Oh; Christian Faul; M Amin Arnaout; Paolo Fiorina; Vineet Gupta; Anna Greka; George W Burke; Peter Mundel
Journal:  N Engl J Med       Date:  2013-11-08       Impact factor: 91.245

3.  Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis.

Authors:  Changli Wei; Shafic El Hindi; Jing Li; Alessia Fornoni; Nelson Goes; Junichiro Sageshima; Dony Maiguel; S Ananth Karumanchi; Hui-Kim Yap; Moin Saleem; Qingyin Zhang; Boris Nikolic; Abanti Chaudhuri; Pirouz Daftarian; Eduardo Salido; Armando Torres; Moro Salifu; Minnie M Sarwal; Franz Schaefer; Christian Morath; Vedat Schwenger; Martin Zeier; Vineet Gupta; David Roth; Maria Pia Rastaldi; George Burke; Phillip Ruiz; Jochen Reiser
Journal:  Nat Med       Date:  2011-07-31       Impact factor: 53.440

4.  A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

Authors:  F Vincenti; B Charpentier; Y Vanrenterghem; L Rostaing; B Bresnahan; P Darji; P Massari; G A Mondragon-Ramirez; M Agarwal; G Di Russo; C-S Lin; P Garg; C P Larsen
Journal:  Am J Transplant       Date:  2010-03       Impact factor: 8.086

Review 5.  Abatacept for rheumatoid arthritis: a Cochrane systematic review.

Authors:  Lara J Maxwell; Jasvinder A Singh
Journal:  J Rheumatol       Date:  2010-01-15       Impact factor: 4.666

Review 6.  Recent progress in the pathophysiology and treatment of FSGS recurrence.

Authors:  P Cravedi; J B Kopp; G Remuzzi
Journal:  Am J Transplant       Date:  2013-01-11       Impact factor: 8.086

7.  Induction of B7-1 in podocytes is associated with nephrotic syndrome.

Authors:  Jochen Reiser; Gero von Gersdorff; Martin Loos; Jun Oh; Katsuhiko Asanuma; Laura Giardino; Maria Pia Rastaldi; Novella Calvaresi; Haruko Watanabe; Karin Schwarz; Christian Faul; Matthias Kretzler; Anne Davidson; Hikaru Sugimoto; Raghu Kalluri; Arlene H Sharpe; Jordan A Kreidberg; Peter Mundel
Journal:  J Clin Invest       Date:  2004-05       Impact factor: 14.808

8.  Toll-like receptor 3 ligand, polyIC, induces proteinuria and glomerular CD80, and increases urinary CD80 in mice.

Authors:  Takuji Ishimoto; Michiko Shimada; Garcia Gabriela; Tomoki Kosugi; Waichi Sato; Pui Y Lee; Miguel A Lanaspa; Christopher Rivard; Shoichi Maruyama; Eduardo H Garin; Richard J Johnson
Journal:  Nephrol Dial Transplant       Date:  2012-12-21       Impact factor: 5.992

9.  Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome.

Authors:  Lionel C Clement; Carmen Avila-Casado; Camille Macé; Elizabeth Soria; Winston W Bakker; Sander Kersten; Sumant S Chugh
Journal:  Nat Med       Date:  2010-12-12       Impact factor: 53.440
  9 in total
  3 in total

1.  Costimulatory blockade: A novel approach to the treatment of glomerular disease?

Authors:  Pasquale Esposito; Teresa Rampino; Antonio Dal Canton
Journal:  World J Methodol       Date:  2015-06-26

2.  Lupus Nephritis IgG Induction of Calcium/Calmodulin-Dependent Protein Kinase IV Expression in Podocytes and Alteration of Their Function.

Authors:  Kunihiro Ichinose; Takeshi Ushigusa; Ayako Nishino; Yosikazu Nakashima; Takahisa Suzuki; Yoshiro Horai; Tomohiro Koga; Shin-ya Kawashiri; Naoki Iwamoto; Mami Tamai; Kazuhiko Arima; Hideki Nakamura; Yoko Obata; Kazuo Yamamoto; Tomoki Origuchi; Tomoya Nishino; Atsushi Kawakami; George C Tsokos
Journal:  Arthritis Rheumatol       Date:  2016-04       Impact factor: 10.995

3.  Increased urinary CD80 excretion and podocyturia in Fabry disease.

Authors:  H Trimarchi; R Canzonieri; A Schiel; C Costales-Collaguazo; J Politei; A Stern; M Paulero; T Rengel; J Andrews; M Forrester; M Lombi; V Pomeranz; R Iriarte; A Muryan; E Zotta; M D Sanchez-Niño; A Ortiz
Journal:  J Transl Med       Date:  2016-10-13       Impact factor: 5.531
  3 in total

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