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Literature DB >> 24373997

Maintenance of a healthy trajectory of the intestinal microbiome during aging: a dietary approach.

Marco Candela¹, Elena Biagi², Patrizia Brigidi², Paul W O'Toole³, Willem M De Vos⁴.

Abstract

Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging.

Entities: Disease Species

Keywords: Diet; Frailty; Healthy aging; Inflammation; Intestinal microbiota

Mesh：

Year: 2013 PMID： 24373997 DOI： 10.1016/j.mad.2013.12.004

Source DB: PubMed Journal: Mech Ageing Dev ISSN： 0047-6374 Impact factor: 5.432

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Cited

24 in total

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7. Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with Lactobacillus rhamnosus GG and the Pilus-Deficient Derivative GG-PB12 on Fecal Microbiota, Metabolism, and Markers of Immune Function: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Elderly (Saimes Study).

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