Literature DB >> 24373516

Long-term results, prognostic factors and cataract surgery after diabetic vitrectomy: a 10-year follow-up study.

Christoffer Ostri1, Anja Lux, Henrik Lund-Andersen, Morten la Cour.   

Abstract

PURPOSE: To report long-term results, prognostic factors and cataract surgery after diabetic vitrectomy.
METHODS: Retrospective review of patient files from a large diabetes centre between 1996 and 2010. Surgical history was obtained from the Danish National Patient Register. Follow-up intervals were 3 months and 1, 3, 5 and 10 years after surgery.
RESULTS: In total, 167 patients had diabetic vitrectomy indicated for non-clearing vitreous haemorrhage (47%) and tractional retinal detachment (53%). The proportion of patients with visual acuity ≥0.3 increased from 29% before surgery to 60% after 3 months (p < 0.001, chi-square test). Median visual acuity increased from 0.06 before surgery to 0.3 after 3 months (p < 0.001, paired signed-rank test) and 0.4 after 1 year (p = 0.009) before stabilizing. No significant long-term prognostic factors were identified for non-clearing vitreous haemorrhage patients. For tractional retinal detachment patients, use of silicone oil was associated with low vision (visual acuity<0.3) after 3 months and 1, 3 and 5 years (all odds ratios >4 and p-values ≤ 0.03, logistic regression). Of the 134 patients who were phakic after surgery, 43% and 29% were phakic after 5 and 10 years, respectively. Use of silicone oil increased the risk of cataract surgery (p = 0.009, log-rank test).
CONCLUSIONS: Most diabetic vitrectomy patients stand to gain visual acuity ≥0.3 after surgery and a stable long-term visual acuity after 1 year. The only consistent long-term predictor of low vision after surgery is use of silicone oil for endotamponade. About 2/3 of phakic patients will subsequently have cataract surgery the first 10 years after diabetic vitrectomy.
© 2013 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  cataract surgery; diabetes; diabetic vitrectomy; long-term results; prognostic factors; results; silicone oil; visual acuity; vitrectomy

Mesh:

Substances:

Year:  2013        PMID: 24373516     DOI: 10.1111/aos.12325

Source DB:  PubMed          Journal:  Acta Ophthalmol        ISSN: 1755-375X            Impact factor:   3.761


  9 in total

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Authors:  Vivian Schreur; Jody Brouwers; Ramon A C Van Huet; Sandra Smeets; Milan Phan; Carel B Hoyng; Eiko K de Jong; B Jeroen Klevering
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9.  Comparison of Retinal Changes Following Silicone Oil and Perfluoropropane Gas Tamponade for Proliferative Diabetic Retinopathy Patients.

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  9 in total

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