Literature DB >> 24373098

Wireless micro current stimulation--an innovative electrical stimulation method for the treatment of patients with leg and diabetic foot ulcers.

Peter G Wirsing1, Alexander D Habrom1, Thomas M Zehnder2, Sandra Friedli2, Marlise Blatti2.   

Abstract

Clinical experience with a new electrical stimulation (ES) technique, the wireless micro current stimulation (WMCS), for the treatment of chronic wounds is described. WMCS transfers the current to any surface wound from a distance, by using oxygen's and nitrogen's ability to exchange electrons. We studied 47 patients with hard-to-heal wounds. Patients with venous, arterial and mixed leg ulcers were predominant; other aetiologies such as diabetic foot lesions, pressure ulcers, vasculitis and pyoderma were also included. WMCS treatment protocol specified treatment twice or thrice per week, for 45-60 minutes per session, with 1·5 μA current intensity. Standard wound care was applied to all patients, including compression bandages, if necessary. Clear progress of wound healing, even after 2 weeks, was observed in all cases. The mean reduction of the wound surface after WMCS treatment was 95% in 8 weeks. Complete healing was achieved within 3 months for the majority of the cases. No clinical side effects were observed. WMCS technology significantly accelerated wound healing for patients with hard-to-heal wounds of different aetiologies. This new therapy offers multiple advantages compared with the previous methods of ES, as it is contactless, free of pain and very easy to use.
© 2013 The Authors. International Wound Journal © 2013 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  Chronic wounds; Diabetic foot; Electrical stimulation; Leg ulcer; Wireless micro current stimulation

Mesh:

Year:  2013        PMID: 24373098      PMCID: PMC7950994          DOI: 10.1111/iwj.12204

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  10 in total

1.  Integrin-dependent human macrophage migration induced by oscillatory electrical stimulation.

Authors:  M R Cho; H S Thatte; R C Lee; D E Golan
Journal:  Ann Biomed Eng       Date:  2000-03       Impact factor: 3.934

2.  Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.

Authors:  Min Zhao; Bing Song; Jin Pu; Teiji Wada; Brian Reid; Guangping Tai; Fei Wang; Aihua Guo; Petr Walczysko; Yu Gu; Takehiko Sasaki; Akira Suzuki; John V Forrester; Henry R Bourne; Peter N Devreotes; Colin D McCaig; Josef M Penninger
Journal:  Nature       Date:  2006-07-27       Impact factor: 49.962

Review 3.  Electrical stimulation for wound healing: a review of evidence from in vitro studies, animal experiments, and clinical trials.

Authors:  Luther C Kloth
Journal:  Int J Low Extrem Wounds       Date:  2005-03       Impact factor: 2.057

4.  Membrane lipids, EGF receptors, and intracellular signals colocalize and are polarized in epithelial cells moving directionally in a physiological electric field.

Authors:  Min Zhao; Jin Pu; John V Forrester; Colin D McCaig
Journal:  FASEB J       Date:  2002-04-10       Impact factor: 5.191

5.  Electric stimulation of protein and DNA synthesis in human fibroblasts.

Authors:  G J Bourguignon; L Y Bourguignon
Journal:  FASEB J       Date:  1987-11       Impact factor: 5.191

6.  Wireless electrical stimulation: an innovative powerful tool for the treatment of a complicated chronic ulcer.

Authors:  Ourania Castana; Aekaterini Dimitrouli; Theodoros Argyrakos; Emilia Theodorakopoulou; Nektarios Stampolidis; Emmanouil Papadopoulos; Athanasios Pallantzas; Ioannis Stasinopoulos; Konstantinos Poulas
Journal:  Int J Low Extrem Wounds       Date:  2013-02-01       Impact factor: 2.057

7.  Effect of electrical stimulation on chronic leg ulcer size and appearance.

Authors:  Pamela E Houghton; Cynthia B Kincaid; Marge Lovell; Karen E Campbell; David H Keast; M Gail Woodbury; Kenneth A Harris
Journal:  Phys Ther       Date:  2003-01

8.  Electrotherapy reoxygenates inframalleolar ischemic wounds on diabetic patients: a case series.

Authors:  Robert J Goldman; Barbara I Brewley; Michael A Golden
Journal:  Adv Skin Wound Care       Date:  2002 May-Jun       Impact factor: 2.347

9.  Local therapy and treatment costs of chronic, venous leg ulcers with electrical stimulation (Dermapulse): a prospective, placebo controlled, double blind trial.

Authors:  Michael Jünger; Andreas Arnold; Daniel Zuder; Hans-Werner Stahl; Susanna Heising
Journal:  Wound Repair Regen       Date:  2008 Jul-Aug       Impact factor: 3.617

10.  Use of wireless microcurrent stimulation for the treatment of diabetes-related wounds: 2 case reports.

Authors:  Adisaputra Ramadhinara; Konstantinos Poulas
Journal:  Adv Skin Wound Care       Date:  2013-01       Impact factor: 2.347

  10 in total
  11 in total

1.  Biochemical and Biophysical Cues in Matrix Design for Chronic and Diabetic Wound Treatment.

Authors:  Yun Xiao; Samad Ahadian; Milica Radisic
Journal:  Tissue Eng Part B Rev       Date:  2016-08-19       Impact factor: 6.389

2.  Feasibility of an electrostimulation system treatment for wound healing: a case series of patients with chronic ulcers in Barbados.

Authors:  Nkemcho Ojeh; Angela Rose; Selma Jackman; Morvillia Applewhaite; Veronica Webster
Journal:  Int Wound J       Date:  2015-03-10       Impact factor: 3.315

3.  ENERGI-F703 gel, as a new topical treatment for diabetic foot and leg ulcers: A multicenter, randomized, double-blind, phase II trial.

Authors:  Jui-Yung Yang; Cha-Chun Chen; Shun-Cheng Chang; Jiun-Ting Yeh; Hui-Fu Huang; Hwang-Chi Lin; Shang-Hsi Lin; Yu-Hsien Lin; Lin-Gwei Wei; Tom J Liu; Shih-Yuan Hung; Hui-Mei Yang; Hui-Hsiu Chang; Chih-Hsin Wang; Yuan-Sheng Tzeng; Chieh-Huei Huang; Chang-Yi Chou; Ying-Sheng Lin; Shih-Yi Yang; Han-Min Chen; Jiun-Tsai Lin; Yi-Fang Cheng; Guang-Huar Young; Chun-Fang Huang; Ya-Chun Kuo; Niann-Tzyy Dai
Journal:  EClinicalMedicine       Date:  2022-07-10

Review 4.  Update on management of diabetic foot ulcers.

Authors:  Estelle Everett; Nestoras Mathioudakis
Journal:  Ann N Y Acad Sci       Date:  2018-01       Impact factor: 5.691

5.  Silver-zinc redox-coupled electroceutical wound dressing disrupts bacterial biofilm.

Authors:  Jaideep Banerjee; Piya Das Ghatak; Sashwati Roy; Savita Khanna; Craig Hemann; Binbin Deng; Amitava Das; Jay L Zweier; Daniel Wozniak; Chandan K Sen
Journal:  PLoS One       Date:  2015-03-24       Impact factor: 3.240

Review 6.  Electrical Stimulation and Cutaneous Wound Healing: A Review of Clinical Evidence.

Authors:  Sara Ud-Din; Ardeshir Bayat
Journal:  Healthcare (Basel)       Date:  2014-10-27

Review 7.  A current affair: electrotherapy in wound healing.

Authors:  Jerome Hunckler; Achala de Mel
Journal:  J Multidiscip Healthc       Date:  2017-04-20

8.  Hypochlorous-Acid-Generating Electrochemical Scaffold for Treatment of Wound Biofilms.

Authors:  Mia Mae Kiamco; Hannah M Zmuda; Abdelrhman Mohamed; Douglas R Call; Yash S Raval; Robin Patel; Haluk Beyenal
Journal:  Sci Rep       Date:  2019-02-25       Impact factor: 4.379

9.  Microcurrent Stimulation Triggers MAPK Signaling and TGF-β1 Release in Fibroblast and Osteoblast-Like Cell Lines.

Authors:  Evangelia Konstantinou; Zoi Zagoriti; Anastasia Pyriochou; Konstantinos Poulas
Journal:  Cells       Date:  2020-08-19       Impact factor: 6.600

Review 10.  Electrically stimulated cell migration and its contribution to wound healing.

Authors:  Guangping Tai; Michael Tai; Min Zhao
Journal:  Burns Trauma       Date:  2018-07-09
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