| Literature DB >> 24372797 |
F Schaumburg1, E A Idelevich, G Peters, A Mellmann, C von Eiff, K Becker.
Abstract
We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004-2005 and 2010-2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim-sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes 003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.Entities:
Keywords: Genotype; Germany; LA-MRSA; methicillin-resistant Staphylococcus aureus; resistance
Mesh:
Substances:
Year: 2014 PMID: 24372797 DOI: 10.1111/1469-0691.12519
Source DB: PubMed Journal: Clin Microbiol Infect ISSN: 1198-743X Impact factor: 8.067