| Literature DB >> 24371724 |
C E Delsing1, C P Bleeker-Rovers1, F L van de Veerdonk1, J Tol2, J W M van der Meer1, B J Kullberg1, M G Netea1.
Abstract
Chronic esophageal candidiasis is an infection that is mostly seen in immunocompromised conditions, among which is chronic mucocutaneous candidiasis (CMC). Recently an association between CMC and esophageal carcinoma has been reported. Here we present two patients with chronic esophageal candidiasis who developed esophageal squamous cell carcinoma and we discuss the etiologic role of Candida-induced nitrosamine production, the loss of STAT1 function and impaired tumor surveillance and T-lymphocyte function in the development of esophageal carcinoma.Entities:
Keywords: Chronic mucocutaneous candidiasis; Esophageal cancer; Esophageal candidiasis
Year: 2012 PMID： 24371724 PMCID： PMC3854631 DOI： 10.1016/j.mmcr.2012.02.003
Source DB: PubMed Journal: Med Mycol Case Rep ISSN： 2211-7539