Literature DB >> 24371575

Identification of a histone derived, putative antimicrobial peptide Himanturin from round whip ray Himantura pastinacoides and its phylogenetic significance.

Naveen Sathyan1, Rosamma Philip1, E R Chaithanya1, P R Anil Kumar1, Swapna P Antony1.   

Abstract

Histone H2A participates in host defense responses by producing antimicrobial peptides (AMPs). The present study deals with identification of a putative antimicrobial sequence, Himanturin from the histone H2A of Round Whip Ray, Himantura pastinacoides. A 204 bp fragment encoding 68 amino acid residues was amplified from cDNA of Round Whip Ray, H. pastinacoides. Himanturin exhibited high similarity to previously reported histone H2A derived AMPs indicating the presence of an antimicrobial sequence motif. Physicochemical properties of Himanturin suggest it to be a potential antimicrobial candidate.

Entities:  

Keywords:  Antimicrobial peptide; Elasmobranch; Himantura pastinacoides; Himanturin; Histone H2A

Year:  2012        PMID: 24371575      PMCID: PMC3862380          DOI: 10.1016/j.rinim.2012.06.001

Source DB:  PubMed          Journal:  Results Immunol        ISSN: 2211-2839


  38 in total

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Journal:  Bioinformatics       Date:  2005-11-13       Impact factor: 6.937

5.  A simple salting out procedure for extracting DNA from human nucleated cells.

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Authors:  Robert D Ward; Tyler S Zemlak; Bronwyn H Innes; Peter R Last; Paul D N Hebert
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Authors:  C B Park; M S Kim; S C Kim
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9.  Pepsin-mediated processing of the cytoplasmic histone H2A to strong antimicrobial peptide buforin I.

Authors:  H S Kim; H Yoon; I Minn; C B Park; W T Lee; M Zasloff; S C Kim
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  6 in total

1.  Molecular Characterisation and Phylogenetic Analysis of a Novel Isoform of Hepatic Antimicrobial Peptide, Hepcidin (Zc-hepc1), from the Coral Fish Moorish idol, Zanclus cornutus (Linnaeus, 1758).

Authors:  E R Chaithanya; Rosamma Philip; Naveen Sathyan; P R Anil Kumar; Sherine Sonia Cubelio; I S Bright Singh
Journal:  Probiotics Antimicrob Proteins       Date:  2013-09       Impact factor: 4.609

2.  Characterization of Histone H2A Derived Antimicrobial Peptides, Harriottins, from Sicklefin Chimaera Neoharriotta pinnata (Schnakenbeck, 1931) and Its Evolutionary Divergence with respect to CO1 and Histone H2A.

Authors:  Naveen Sathyan; Rosamma Philip; E R Chaithanya; P R Anil Kumar; V N Sanjeevan; I S Bright Singh
Journal:  ISRN Mol Biol       Date:  2013-06-02

3.  Immune gene discovery by expressed sequence tag (EST) analysis of hemocytes in the ridgetail white prawn Exopalaemon carinicauda.

Authors:  Yafei Duan; Ping Liu; Jitao Li; Jian Li; Ping Chen
Journal:  Fish Shellfish Immunol       Date:  2012-10-22       Impact factor: 4.581

4.  Molecular Characterization and Phylogenetic Analysis of a Histone-Derived Antimicrobial Peptide Teleostin from the Marine Teleost Fishes, Tachysurus jella and Cynoglossus semifasciatus.

Authors:  E R Chaithanya; Rosamma Philip; Naveen Sathyan; P R Anil Kumar
Journal:  ISRN Mol Biol       Date:  2013-03-03

5.  Identification and Molecular Characterization of Molluskin, a Histone-H2A-Derived Antimicrobial Peptide from Molluscs.

Authors:  Naveen Sathyan; Rosamma Philip; E R Chaithanya; P R Anil Kumar
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Review 6.  Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders.

Authors:  Peter Szatmary; Wei Huang; David Criddle; Alexei Tepikin; Robert Sutton
Journal:  J Cell Mol Med       Date:  2018-08-07       Impact factor: 5.310

  6 in total

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