Literature DB >> 24370963

Whoonga and the abuse and diversion of antiretrovirals in Soweto, South Africa.

Kathryn Rough1, Janan Dietrich, Thandekile Essien, David J Grelotti, David R Bansberg, Glenda Gray, Ingrid T Katz.   

Abstract

Media reports have described recreational use of HIV antiretroviral medication in South Africa, but little has been written about this phenomenon in the scientific literature. We present original, qualitative data from eight semi-structured interviews that characterize recreational antiretroviral use in Soweto, South Africa. Participants reported that antiretrovirals, likely efavirenz, are crushed, mixed with illicit drugs (in a mixture known as whoonga), and smoked. They described medications being stolen from patients and expressed concern that antiretroviral abuse jeopardized the safety of both patients and users. Further studies are needed to understand the prevalence, patterns, and consequences of antiretroviral abuse and diversion.

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Year:  2014        PMID: 24370963      PMCID: PMC4047174          DOI: 10.1007/s10461-013-0683-x

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  5 in total

1.  Manic syndrome associated with efavirenz overdose.

Authors:  J Blanch; B Corbella; F García; E Parellada; J M Gatell
Journal:  Clin Infect Dis       Date:  2001-07-15       Impact factor: 9.079

2.  A case of voluntary intoxication with efavirenz and lamivudine.

Authors:  Rémy T Boscacci; Thierry Buclin; Hansjakob Furrer; Christoph A Fux
Journal:  AIDS       Date:  2006-06-12       Impact factor: 4.177

3.  Whoonga: potential recreational use of HIV antiretroviral medication in South Africa.

Authors:  David J Grelotti; Elizabeth F Closson; Jennifer A Smit; Zonke Mabude; Lynn T Matthews; Steven A Safren; David R Bangsberg; Matthew J Mimiaga
Journal:  AIDS Behav       Date:  2014-03

4.  Mechanisms of prescription drug diversion among drug-involved club- and street-based populations.

Authors:  James A Inciardi; Hilary L Surratt; Steven P Kurtz; Theodore J Cicero
Journal:  Pain Med       Date:  2007-03       Impact factor: 3.750

5.  Pretreatment antiretroviral exposure from recreational use.

Authors:  David J Grelotti; Elizabeth F Closson; Matthew J Mimiaga
Journal:  Lancet Infect Dis       Date:  2013-01       Impact factor: 25.071

  5 in total
  17 in total

1.  Antiretroviral drug use and HIV drug resistance among MSM and transgender women in sub-Saharan Africa.

Authors:  Yinfeng Zhang; Jessica M Fogel; Xu Guo; William Clarke; Autumn Breaud; Vanessa Cummings; Erica L Hamilton; Arthur Ogendo; Noel Kayange; Ravindre Panchia; Karen Dominguez; Ying Q Chen; Theodorus Sandfort; Susan H Eshleman
Journal:  AIDS       Date:  2018-06-19       Impact factor: 4.177

2.  Antiretroviral Drug Use in a Cross-Sectional Population Survey in Africa: NIMH Project Accept (HPTN 043).

Authors:  Jessica M Fogel; William Clarke; Michal Kulich; Estelle Piwowar-Manning; Autumn Breaud; Matthew T Olson; Mark A Marzinke; Oliver Laeyendecker; Agnès Fiamma; Deborah Donnell; Jessie K K Mbwambo; Linda Richter; Glenda Gray; Michael Sweat; Thomas J Coates; Susan H Eshleman; Alfred H Chingono
Journal:  J Acquir Immune Defic Syndr       Date:  2017-02-01       Impact factor: 3.731

3.  Antiretroviral Drug Use and HIV Drug Resistance Among Young Women in Rural South Africa: HPTN 068.

Authors:  Yinfeng Zhang; Mariya V Sivay; Sarah E Hudelson; William Clarke; Autumn Breaud; Jing Wang; Estelle Piwowar-Manning; Yaw Agyei; Jessica M Fogel; Erica L Hamilton; Amanda Selin; Catherine MacPhail; Kathleen Kahn; Francesc Xavier Gómez-Olivé; James P Hughes; Audrey Pettifor; Susan H Eshleman
Journal:  J Acquir Immune Defic Syndr       Date:  2018-11-01       Impact factor: 3.731

4.  Recreational ART use among individuals living with HIV/AIDS in South Africa: Examining longitudinal ART initiation and viral suppression.

Authors:  Jessica F Magidson; Hari S Iyer; Kristen S Regenauer; David J Grelotti; Janan J Dietrich; Ingrid Courtney; Gugu Tshabalala; Catherine Orrell; Glenda E Gray; David R Bangsberg; Ingrid T Katz
Journal:  Drug Alcohol Depend       Date:  2019-03-22       Impact factor: 4.492

Review 5.  A Systematic Review of Risk Factors and Consequences of Nyaope Usage: The Illicit Street Drug Containing HIV Antiretrovirals.

Authors:  Karan Varshney; Samuel D Browning; Sujit K Debnath; Pavan Shet; Darshan Shet
Journal:  AIDS Behav       Date:  2022-07-27

6.  Recreational Use of HIV Antiretroviral Medication and Implications for HIV Pre-exposure Prophylaxis and Treatment.

Authors:  Caroline Kuo; Danielle Giovenco; Teresa DeAtley; Jackie Hoare; Kristen Underhill; Millicent Atujuna; Catherine Mathews; Dan J Stein; Larry K Brown; Don Operario
Journal:  AIDS Behav       Date:  2020-09

7.  Trajectories of initiation for the heroin-based drug whoonga - qualitative evidence from South Africa.

Authors:  Griffin A Tyree; Nzwakie Mosery; Elizabeth F Closson; Zonke Mabude; Carol du Toit; David R Bangsberg; Steven A Safren; Kenneth H Mayer; Jennifer A Smit; Matthew J Mimiaga; David J Grelotti
Journal:  Int J Drug Policy       Date:  2020-06-12

8.  Antiretroviral therapy initiation and adherence in rural South Africa: community health workers' perspectives on barriers and facilitators.

Authors:  Kelsey B Loeliger; Linda M Niccolai; Lillian N Mtungwa; Anthony Moll; Sheela V Shenoi
Journal:  AIDS Care       Date:  2016-04-04

9.  "You are not alone": a qualitative study to explore barriers to ART initiation and implications for a proposed community-based youth treatment club among young adults newly diagnosed with HIV in South Africa.

Authors:  Maria F Nardell; Yeonsoo Sara Lee; Elzette Rousseau; Robin Julies; Portia Klaas; Prisca Vundhla; Lisa Butler; Ingrid V Bassett; Claude A Mellins; Linda-Gail Bekker; Ingrid T Katz
Journal:  AIDS Care       Date:  2020-12-21

10.  Perceptions matter: Narratives of contraceptive implant robbery in Cape Town, South Africa.

Authors:  Emily A Krogstad; Millicent Atujuna; Elizabeth T Montgomery; Alexandra M Minnis; Chelsea Morroni; Linda-Gail Bekker
Journal:  Cult Health Sex       Date:  2020-03-27
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