Literature DB >> 2437096

Establishment of a rat nasal epithelial tumor cell line.

A T Hood, D Currie, S J Garte.   

Abstract

A new cell line designated NAS 2BL has been established from a rat nasal tumor induced by inhalation of the direct-acting carcinogen methylmethane sulfonate. The cells are epithelial in morphology, have a generation time of 34 h, require 10% fetal bovine serum for optimal growth, and exhibit keratinization at confluence. The karyotype is aneuploid, with several marker chromosomes, and the cells are transformed by the criterion of nude mouse tumorigenicity.

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Year:  1987        PMID： 2437096     DOI： 10.1007/bf02623710

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol        ISSN： 0883-8364


  10 in total

1.  Tumors of the respiratory tract induced by inhalation of bis(chloromethyl)ether.

Authors:  S Laskin; M Kuschner; R T Drew; V P Cappiello; N Nelson
Journal:  Arch Environ Health       Date:  1971-08

2.  Polymorphic variants in human chromosome 15.

Authors:  T R Chen; M L Kao; J Marks; Y Y Chen
Journal:  Am J Med Genet       Date:  1981

3.  Comparative morphometry of the nasal cavity in rats and mice.

Authors:  E A Gross; J A Swenberg; S Fields; J A Popp
Journal:  J Anat       Date:  1982-08       Impact factor: 2.610

4.  Differential effects of phorbol ester on the beta-adrenergic response of normal and ras-transformed NIH3T3 cells.

Authors:  S J Garte
Journal:  Biochem Biophys Res Commun       Date:  1985-12-17       Impact factor: 3.575

5.  Gaseous formaldehyde and hydrogen chloride induction of nasal cancer in the rat.

Authors:  R E Albert; A R Sellakumar; S Laskin; M Kuschner; N Nelson; C A Snyder
Journal:  J Natl Cancer Inst       Date:  1982-04       Impact factor: 13.506

6.  Carcinogen specificity in the activation of transforming genes by direct-acting alkylating agents.

Authors:  S J Garte; A T Hood; A E Hochwalt; P D'Eustachio; C A Snyder; A Segal; R E Albert
Journal:  Carcinogenesis       Date:  1985-12       Impact factor: 4.944

7.  Effects of formaldehyde exposure on the extractability of DNA from proteins in the rat nasal mucosa.

Authors:  M Casanova-Schmitz; H D Heck
Journal:  Toxicol Appl Pharmacol       Date:  1983-08       Impact factor: 4.219

8.  Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor.

Authors:  J A Swenberg; W D Kerns; R I Mitchell; E J Gralla; K L Pavkov
Journal:  Cancer Res       Date:  1980-09       Impact factor: 12.701

9.  Inhalation carcinogenicity of epichlorohydrin in noninbred Sprague-Dawley rats.

Authors:  S Laskin; A R Sellakumar; M Kuschner; N Nelson; S La Mendola; G M Rusch; G V Katz; N C Dulak; R E Albert
Journal:  J Natl Cancer Inst       Date:  1980-10       Impact factor: 13.506

10.  Isolation and long-term culture of rat, rabbit, and human nasal turbinate epithelial cells.

Authors:  V E Steele; J T Arnold
Journal:  In Vitro Cell Dev Biol       Date:  1985-12
  10 in total
  1 in total

Review 1.  The use of cultured epithelial and endothelial cells for drug transport and metabolism studies.

Authors:  K L Audus; R L Bartel; I J Hidalgo; R T Borchardt
Journal:  Pharm Res       Date:  1990-05       Impact factor: 4.200
  1 in total

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