| Literature DB >> 2437028 |
Abstract
The synthesis of proteoheparan sulfate in hepatocytes is positively regulated under acute-phase conditions produced either by turpentine or deep back incision. In both cases the incorporation of [35S]sulfate and [14C]glucosamine is doubled during a 4-h incubation period if compared with control rat hepatocytes. Neither the fractional secretion rate of heparan sulfate into the medium (less than 0.1 of cell-associated glycosaminoglycans) nor the composition of newly formed proteoglycans in hepatocytes are affected during acute phase reaction.Entities:
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Year: 1987 PMID： 2437028 DOI： 10.1007/bf00917770
Source DB: PubMed Journal: Inflammation ISSN： 0360-3997 Impact factor: 4.092