| Literature DB >> 24369799 |
Abstract
In 2013, several themes emerged: (1) a dedicated search for new therapies using new mechanisms; (2) the importance of the plasticity of the immune system (eg, that molecules that mediate inflammation in one setting can promote its resolution and return to homeostasis in other circumstances); (3) the complex role of viruses in asthma exacerbations; (4) the similarities and differences among asthma, asthma in smokers, and chronic obstructive pulmonary disease; and (5) the importance of understanding asthma phenotypes and their stability over time. Once new therapeutics pass the initial clinical trials, patient-oriented and real-world research will be needed.Entities:
Keywords: ACQ; Alveolar fraction of exhaled nitric oxide; Asthma; Asthma Control Questionnaire; C(alv)NO; COPD; CRTH2; Chemoattractant receptor homologous molecule expressed on T(H)2 cells; Chronic obstructive pulmonary disease; EBC; Exhaled breath condensate; Feno; Fraction of exhaled nitric oxide; ICS; Inhaled corticosteroid; LABA; Long-acting β-agonist; OA; Occupational asthma; PGD(2); PROM; Patient-reported outcome measure; Prostaglandin D(2); SLIT; Sublingual immunotherapy; TLR; Toll-like receptor; WEA; WRA; Work-exacerbated asthma; Work-related asthma; adults; asthma management; inhaled corticosteroids
Mesh：
Substances：
Year: 2014 PMID： 24369799 DOI： 10.1016/j.jaci.2013.11.005
Source DB: PubMed Journal: J Allergy Clin Immunol ISSN： 0091-6749 Impact factor: 10.793