Literature DB >> 24369366

Feasibility and efficacy of a computer-based intervention aimed at preventing reading decoding deficits among children undergoing active treatment for medulloblastoma: results of a randomized trial.

Shawna L Palmer1, Laurie Leigh, Susan C Ellison, Arzu Onar-Thomas, Shengjie Wu, Ibrahim Qaddoumi, Gregory T Armstrong, Karen Wright, Cynthia Wetmore, Alberto Broniscer, Amar Gajjar.   

Abstract

OBJECTIVE: To investigate the feasibility of a computer-based reading intervention completed by patients diagnosed with a brain tumor.
METHODS: Patients were randomized to the intervention (n = 43) or standard of care group (n = 38). The intervention consisted of 30 sessions using Fast ForWord® exercises in a game-like format. Change in reading decoding scores over time since diagnosis was examined. Gender, race, parent education, parent marital status, and age at diagnosis were examined as covariates.
RESULTS: 17 patients (39.5%) were able to complete the target goal of 30 intervention sessions. Females had significantly greater training time than males (p = .022). Age at diagnosis was associated with average training time/session for females (r = .485, p = .041). No significant differences were found in reading scores between the randomized groups.
CONCLUSIONS: The study was well accepted by families and adherence by patients undergoing radiation therapy for medulloblastoma was moderate. Suggestions for improved methodology are discussed.

Entities:  

Keywords:  academic functioning; cancer and oncology; children; cognitive assessment; intervention outcome; longitudinal research; neuropsychology

Mesh:

Year:  2013        PMID: 24369366      PMCID: PMC3994317          DOI: 10.1093/jpepsy/jst095

Source DB:  PubMed          Journal:  J Pediatr Psychol        ISSN: 0146-8693


  21 in total

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Journal:  Nature       Date:  1997-05-08       Impact factor: 49.962

6.  Language comprehension in language-learning impaired children improved with acoustically modified speech.

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9.  Immediate neurocognitive effects of methylphenidate on learning-impaired survivors of childhood cancer.

Authors:  S J Thompson; L Leigh; R Christensen; X Xiong; L E Kun; R L Heideman; W E Reddick; A Gajjar; T Merchant; C H Pui; M M Hudson; R K Mulhern
Journal:  J Clin Oncol       Date:  2001-03-15       Impact factor: 44.544

10.  Temporal processing deficits of language-learning impaired children ameliorated by training.

Authors:  M M Merzenich; W M Jenkins; P Johnston; C Schreiner; S L Miller; P Tallal
Journal:  Science       Date:  1996-01-05       Impact factor: 47.728

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  8 in total

1.  Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach.

Authors:  Taryn B Fay-McClymont; Danielle M Ploetz; Don Mabbott; Karin Walsh; Amy Smith; Susan N Chi; Elizabeth Wells; Jennifer Madden; Ashley Margol; Jonathan Finlay; Mark W Kieran; Douglas Strother; Girish Dhall; Roger J Packer; Nicholas K Foreman; E Bouffet; Lucie Lafay-Cousin
Journal:  J Neurooncol       Date:  2017-04-12       Impact factor: 4.130

2.  Cognitive Implications of Ototoxicity in Pediatric Patients With Embryonal Brain Tumors.

Authors:  Traci W Olivier; Johnnie K Bass; Jason M Ashford; Rebecca Beaulieu; Sarah M Scott; Jane E Schreiber; Shawna Palmer; Donald J Mabbott; Michelle A Swain; Melanie Bonner; Robyn Boyle; Mary Lynn Chapeiski; Karen D Evankovich; Carol L Armstrong; Sarah J Knight; Shengjie Wu; Arzu Onar-Thomas; Amar Gajjar; Heather M Conklin
Journal:  J Clin Oncol       Date:  2019-05-02       Impact factor: 44.544

3.  Functional MRI in medulloblastoma survivors supports prophylactic reading intervention during tumor treatment.

Authors:  Ping Zou; Heather M Conklin; Matthew A Scoggins; Yimei Li; Xingyu Li; Melissa M Jones; Shawna L Palmer; Amar Gajjar; Robert J Ogg
Journal:  Brain Imaging Behav       Date:  2016-03       Impact factor: 3.978

4.  Working memory abilities among children treated for medulloblastoma: parent report and child performance.

Authors:  Sarah J Knight; Heather M Conklin; Shawna L Palmer; Jane E Schreiber; Carol L Armstrong; Dana Wallace; Melanie Bonner; Michelle A Swain; Karen D Evankovich; Donald J Mabbott; Robyn Boyle; Qinlei Huang; Hui Zhang; Vicki A Anderson; Amar Gajjar
Journal:  J Pediatr Psychol       Date:  2014-03-12

5.  Sophoridine suppresses cell growth in human medulloblastoma through FoxM1, NF-κB and AP-1.

Authors:  Zhensong Yue; Tongguo Si; Zhanyu Pan; Wenfeng Cao; Zhuchen Yan; Zhansheng Jiang; Huaqiang Ouyang
Journal:  Oncol Lett       Date:  2017-10-19       Impact factor: 2.967

6.  Neuroimaging Biomarkers and Neurocognitive Outcomes in Pediatric Medulloblastoma Patients: a Systematic Review.

Authors:  Maarten Wauters; Anne Uyttebroeck; Liesbeth De Waele; Charlotte Sleurs; Sandra Jacobs
Journal:  Cerebellum       Date:  2021-01-08       Impact factor: 3.847

Review 7.  Computer-Based Cognitive Training in Children with Primary Brain Tumours: A Systematic Review.

Authors:  Francesco Sciancalepore; Leonardo Tariciotti; Giulia Remoli; Danilo Menegatti; Andrea Carai; Giuseppe Petruzzellis; Kiersten P Miller; Francesco Delli Priscoli; Alessandro Giuseppi; Roberto Premuselli; Alberto E Tozzi; Angela Mastronuzzi; Nicola Vanacore; Eleonora Lacorte; Allena-Mente Study Group
Journal:  Cancers (Basel)       Date:  2022-08-11       Impact factor: 6.575

Review 8.  Educational Pain Points for Pediatric Brain Tumor Survivors: Review of Risks and Remedies.

Authors:  Peter L Stavinoha; Thuy Trinh-Wong; Laura N Rodriguez; Chawncey M Stewart; Kris Frost
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  8 in total

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