Literature DB >> 24368636

Metabolic thrift and the genetic basis of human obesity.

Robert W Oʼrourke1.   

Abstract

Evolution has molded metabolic thrift within humans, a genetic heritage that, when thrust into our modern "obesogenic" environment, creates the current obesity crisis. Modern genetic analysis has identified genetic and epigenetic contributors to obesity, an understanding of which will guide the development of environmental, pharmacologic, and genetic therapeutic interventions.

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Year:  2014        PMID： 24368636      PMCID： PMC4057799          DOI： 10.1097/SLA.0000000000000361

Source DB:  PubMed          Journal:  Ann Surg        ISSN： 0003-4932            Impact factor:   12.969


  81 in total

1.  Genetic influences on growth traits of BMI: a longitudinal study of adult twins.

Authors:  Jacob v B Hjelmborg; Corrado Fagnani; Karri Silventoinen; Matt McGue; Maarit Korkeila; Kaare Christensen; Aila Rissanen; Jaakko Kaprio
Journal:  Obesity (Silver Spring)       Date:  2008-01-31       Impact factor: 5.002

2.  Heritability of obesity-related phenotypes and association with adiponectin gene polymorphisms in the Chinese national twin registry.

Authors:  Juan Lee; Li Chen; Harold Snieder; Da F Chen; Li M Lee; Gai F Liu; Ting Wu; Xun Tang; Si Y Zhan; Wei H Cao; Jun Lv; Wen J Gao; Yong H Hu
Journal:  Ann Hum Genet       Date:  2010-02-18       Impact factor: 1.670

3.  Circadian disruption leads to insulin resistance and obesity.

Authors:  Shu-qun Shi; Tasneem S Ansari; Owen P McGuinness; David H Wasserman; Carl Hirschie Johnson
Journal:  Curr Biol       Date:  2013-02-21       Impact factor: 10.834

4.  Bergmann's rule and the thrifty genotype.

Authors:  J R Bindon; P T Baker
Journal:  Am J Phys Anthropol       Date:  1997-10       Impact factor: 2.868

5.  Thrifty genes for obesity, an attractive but flawed idea, and an alternative perspective: the 'drifty gene' hypothesis.

Authors:  J R Speakman
Journal:  Int J Obes (Lond)       Date:  2008-10-14       Impact factor: 5.095

6.  DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific.

Authors:  Elmar W Tobi; L H Lumey; Rudolf P Talens; Dennis Kremer; Hein Putter; Aryeh D Stein; P Eline Slagboom; Bastiaan T Heijmans
Journal:  Hum Mol Genet       Date:  2009-08-04       Impact factor: 6.150

7.  Positional cloning of the mouse obese gene and its human homologue.

Authors:  Y Zhang; R Proenca; M Maffei; M Barone; L Leopold; J M Friedman
Journal:  Nature       Date:  1994-12-01       Impact factor: 49.962

8.  Assortative mating for obesity.

Authors:  John R Speakman; Kurosh Djafarian; Joanne Stewart; Diane M Jackson
Journal:  Am J Clin Nutr       Date:  2007-08       Impact factor: 7.045

9.  Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women.

Authors:  An Pan; Eva S Schernhammer; Qi Sun; Frank B Hu
Journal:  PLoS Med       Date:  2011-12-06       Impact factor: 11.069

10.  A genome-wide methylation study on obesity: differential variability and differential methylation.

Authors:  Xiaojing Xu; Shaoyong Su; Vernon A Barnes; Carmen De Miguel; Jennifer Pollock; Dennis Ownby; Hidong Shi; Haidong Zhu; Harold Snieder; Xiaoling Wang
Journal:  Epigenetics       Date:  2013-04-17       Impact factor: 4.528
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  9 in total

1.  Biphasic alterations in coronary smooth muscle Ca(2+) regulation in a repeat cross-sectional study of coronary artery disease severity in metabolic syndrome.

Authors:  Mikaela L McKenney-Drake; Stacey D Rodenbeck; Meredith K Owen; Kyle A Schultz; Mouhamad Alloosh; Johnathan D Tune; Michael Sturek
Journal:  Atherosclerosis       Date:  2016-03-26       Impact factor: 5.162

Review 2.  Anti-ghrelin antibodies in appetite suppression: recent advances in obesity pharmacotherapy.

Authors:  Velimir Altabas; Vanja Zjačić-Rotkvić
Journal:  Immunotargets Ther       Date:  2015-07-09

Review 3.  Physiological adaptations to weight loss and factors favouring weight regain.

Authors:  F L Greenway
Journal:  Int J Obes (Lond)       Date:  2015-04-21       Impact factor: 5.095

Review 4.  International society of sports nutrition position stand: diets and body composition.

Authors:  Alan A Aragon; Brad J Schoenfeld; Robert Wildman; Susan Kleiner; Trisha VanDusseldorp; Lem Taylor; Conrad P Earnest; Paul J Arciero; Colin Wilborn; Douglas S Kalman; Jeffrey R Stout; Darryn S Willoughby; Bill Campbell; Shawn M Arent; Laurent Bannock; Abbie E Smith-Ryan; Jose Antonio
Journal:  J Int Soc Sports Nutr       Date:  2017-06-14       Impact factor: 5.150

5.  Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice.

Authors:  Nivedita Seshadri; Michael E Jonasson; Kristin L Hunt; Bo Xiang; Steven Cooper; Michael B Wheeler; Vernon W Dolinsky; Christine A Doucette
Journal:  Mol Metab       Date:  2017-04-27       Impact factor: 7.422

6.  Early in life effects and heredity: reconciling neo-Darwinism with neo-Lamarckism under the banner of the inclusive evolutionary synthesis.

Authors:  Étienne Danchin; Arnaud Pocheville; Philippe Huneman
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-04-15       Impact factor: 6.237

7.  When the "satisficing" is the new "fittest": how a proscriptive definition of adaptation can change our view of cognition and culture.

Authors:  Valentin Magnon; Bruno Corbara
Journal:  Naturwissenschaften       Date:  2022-08-12

8.  Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways.

Authors:  Michael C Ryczko; Judy Pawling; Rui Chen; Anas M Abdel Rahman; Kevin Yau; Julia K Copeland; Cunjie Zhang; Anu Surendra; David S Guttman; Daniel Figeys; James W Dennis
Journal:  Sci Rep       Date:  2016-03-14       Impact factor: 4.379

Review 9.  Epigenetics in the Uterine Environment: How Maternal Diet and ART May Influence the Epigenome in the Offspring with Long-Term Health Consequences.

Authors:  Irene Peral-Sanchez; Batoul Hojeij; Diego A Ojeda; Régine P M Steegers-Theunissen; Sandrine Willaime-Morawek
Journal:  Genes (Basel)       Date:  2021-12-23       Impact factor: 4.096
  9 in total

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