Literature DB >> 2436686

A monoclonal antibody reacting with human basophils.

M P Bodger, G L Mounsey, J Nelson, P H Fitzgerald.   

Abstract

Bsp-1 is an IgM murine monoclonal antibody raised against the human erythroblastic leukemia cell line (HEL) that reacts with basophils but not neutrophils or eosinophils. Western blotting techniques showed that Bsp-1 reacts with a 45-kilodalton surface antigen on HEL cells. The distribution of Bsp-1 antigen on leukemic cells is confined to a basophilic leukemia cell line, KU812, chronic myeloid leukemia with basophilia, and some cases of acute undifferentiated leukemia. Bsp-1 might therefore be a useful reagent for the study of basophil function and differentiation.

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Year:  1987        PMID： 2436686

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  4 in total

1.  Stem cell factor-dependent human cord blood derived mast cells express alpha- and beta-tryptase, heparin and chondroitin sulphate.

Authors:  G Nilsson; T Blom; I Harvima; M Kusche-Gullberg; K Nilsson; L Hellman
Journal:  Immunology       Date:  1996-06       Impact factor: 7.397

Review 2.  Surface proteins and glycoproteins of human leucocytes.

Authors:  V Horejsí; V Bazil
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

3.  Phenotypic characterization of stem cell factor-dependent human foetal liver-derived mast cells.

Authors:  G Nilsson; K Forsberg; M P Bodger; L K Ashman; K M Zsebo; T Ishizaka; A M Irani; L B Schwartz
Journal:  Immunology       Date:  1993-06       Impact factor: 7.397

4.  Basophils are increased and express increased levels of interleukin-4 in the parotid lesions of Kimura disease.

Authors:  Manabu Nonaka; Eri Sakitani; Erika Ono; Yukie Yamamura; Yukako Seo; Noriyuki Shibata; Ruby Pawankar; Toshio Yoshihara
Journal:  Asia Pac Allergy       Date:  2017-10-23
  4 in total

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