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Literature DB >> 24364583

Allosteric modulators hit the TSH receptor.

Terry F Davies¹, M Rejwan Ali, Rauf Latif.

Abstract

Entities: Gene

Mesh：

Substances：

Year: 2014 PMID： 24364583 PMCID： PMC3868806 DOI： 10.1210/en.2013-2079

Source DB: PubMed Journal: Endocrinology ISSN： 0013-7227 Impact factor: 4.736

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44 in total

1. Recombinant human thyroid-stimulating hormone: initial bioactivity assessment using human fetal thyroid cells.

Authors: G K Huber; P Fong; E S Concepcion; T F Davies
Journal: J Clin Endocrinol Metab Date: 1991-06 Impact factor: 5.958

Review 2. The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies.

Authors: B Rapoport; G D Chazenbalk; J C Jaume; S M McLachlan
Journal: Endocr Rev Date: 1998-12 Impact factor: 19.871

3. Comparison of administration of recombinant human thyrotropin with withdrawal of thyroid hormone for radioactive iodine scanning in patients with thyroid carcinoma.

Authors: P W Ladenson; L E Braverman; E L Mazzaferri; F Brucker-Davis; D S Cooper; J R Garber; F E Wondisford; T F Davies; L J DeGroot; G H Daniels; D S Ross; B D Weintraub
Journal: N Engl J Med Date: 1997-09-25 Impact factor: 91.245

4. Thyroid-stimulating immunoglobulins in Graves' disease.

Authors: B R Smith; R Hall
Journal: Lancet Date: 1974-08-24 Impact factor: 79.321

5. Increased sulfatation of orbital glycosaminoglycans in Graves' ophthalmopathy.

Authors: C Hansen; R Rouhi; G Förster; G J Kahaly
Journal: J Clin Endocrinol Metab Date: 1999-04 Impact factor: 5.958

Review 6. Activating mutations of TSH receptor.

Authors: P Rodien; S-C Ho; V Vlaeminck; G Vassart; S Costagliola
Journal: Ann Endocrinol (Paris) Date: 2003-02 Impact factor: 2.478

7. The shed thyrotropin receptor is primarily a carboxyl terminal truncated form of the A subunit, not the entire A subunit.

Authors: K Tanaka; G D Chazenbalk; S M McLachlan; B Rapoport
Journal: Mol Cell Endocrinol Date: 1999-04-25 Impact factor: 4.102

Allosteric modulators hit the TSH receptor.

1. Recombinant human thyroid-stimulating hormone: initial bioactivity assessment using human fetal thyroid cells.

Review 2. The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies.

3. Comparison of administration of recombinant human thyrotropin with withdrawal of thyroid hormone for radioactive iodine scanning in patients with thyroid carcinoma.

4. Thyroid-stimulating immunoglobulins in Graves' disease.

5. Increased sulfatation of orbital glycosaminoglycans in Graves' ophthalmopathy.

Review 6. Activating mutations of TSH receptor.

7. The shed thyrotropin receptor is primarily a carboxyl terminal truncated form of the A subunit, not the entire A subunit.

8. TSH is a negative regulator of skeletal remodeling.

9. A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice.

Review 10. TSH receptor expression in orbital tissue and its role in the pathogenesis of Graves' ophthalmopathy.

1. New small molecule agonists to the thyrotropin receptor.

Review 2. Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies.

3. The "TSH Receptor Glo Assay" - A High-Throughput Detection System for Thyroid Stimulation.

4. Molecular Insights into the Transmembrane Domain of the Thyrotropin Receptor.