Literature DB >> 24363451

Determinants of GH resistance in malnutrition.

Pouneh K Fazeli1, Anne Klibanski.   

Abstract

States of undernutrition are characterized by GH resistance. Decreased total energy intake, as well as isolated protein-calorie malnutrition and isolated nutrient deficiencies, result in elevated GH levels and low levels of IGF1. We review various states of malnutrition and a disease state characterized by chronic undernutrition - anorexia nervosa - and discuss possible mechanisms contributing to the state of GH resistance, including fibroblast growth factor 21 and Sirtuin 1. We conclude by examining the hypothesis that GH resistance is an adaptive response to states of undernutrition, in order to maintain euglycemia and preserve energy.

Entities:  

Keywords:  IGF; growth hormone; neuroendocrinology; pituitary

Mesh：

Substances：

Year:  2014        PMID： 24363451      PMCID： PMC3994591          DOI： 10.1530/JOE-13-0477

Source DB:  PubMed          Journal:  J Endocrinol        ISSN： 0022-0795            Impact factor:   4.286


  79 in total

1.  Determinants of IGF1 and GH across the weight spectrum: from anorexia nervosa to obesity.

Authors:  D J Brick; A V Gerweck; E Meenaghan; E A Lawson; M Misra; P Fazeli; W Johnson; A Klibanski; K K Miller
Journal:  Eur J Endocrinol       Date:  2010-05-25       Impact factor: 6.664

2.  Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.

Authors:  Tong-Jin Zhao; Guosheng Liang; Robert Lin Li; Xuefen Xie; Mark W Sleeman; Andrew J Murphy; David M Valenzuela; George D Yancopoulos; Joseph L Goldstein; Michael S Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-15       Impact factor: 11.205

3.  Effect of a high-protein diet on ghrelin, growth hormone, and insulin-like growth factor-I and binding proteins 1 and 3 in subjects with type 2 diabetes mellitus.

Authors:  Mary Carol Gannon; Frank Quentin Nuttall
Journal:  Metabolism       Date:  2011-03-15       Impact factor: 8.694

4.  Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study.

Authors:  Pouneh K Fazeli; Elizabeth A Lawson; Rajani Prabhakaran; Karen K Miller; Daniel A Donoho; David R Clemmons; David B Herzog; Madhusmita Misra; Anne Klibanski
Journal:  J Clin Endocrinol Metab       Date:  2010-07-28       Impact factor: 5.958

5.  Fibroblast growth factor-21 may mediate growth hormone resistance in anorexia nervosa.

Authors:  Pouneh K Fazeli; Madhusmita Misra; Mark Goldstein; Karen K Miller; Anne Klibanski
Journal:  J Clin Endocrinol Metab       Date:  2009-11-19       Impact factor: 5.958

6.  Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity.

Authors:  M Mraz; M Bartlova; Z Lacinova; D Michalsky; M Kasalicky; D Haluzikova; M Matoulek; I Dostalova; V Humenanska; M Haluzik
Journal:  Clin Endocrinol (Oxf)       Date:  2008-12-11       Impact factor: 3.478

7.  Bioactive insulin-like growth factor-I in obesity.

Authors:  J Frystyk; D J Brick; A V Gerweck; A L Utz; K K Miller
Journal:  J Clin Endocrinol Metab       Date:  2009-05-26       Impact factor: 5.958

8.  Growth hormone/insulin-like growth factor I axis, glucose metabolism, and lypolisis but not leptin show some degree of refractoriness to short-term fasting in acromegaly.

Authors:  S Grottoli; V Gasco; A Mainolfi; G Beccuti; G Corneli; G Aimaretti; C Dieguez; F Casanueva; E Ghigo
Journal:  J Endocrinol Invest       Date:  2008-12       Impact factor: 4.256

9.  FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response.

Authors:  Matthew J Potthoff; Takeshi Inagaki; Santhosh Satapati; Xunshan Ding; Tianteng He; Regina Goetz; Moosa Mohammadi; Brian N Finck; David J Mangelsdorf; Steven A Kliewer; Shawn C Burgess
Journal:  Proc Natl Acad Sci U S A       Date:  2009-06-16       Impact factor: 11.205

10.  The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction.

Authors:  Chun-Xia Yi; Kristy M Heppner; Henriette Kirchner; Jenny Tong; Maximillian Bielohuby; Bruce D Gaylinn; Timo D Müller; Erin Bartley; Harold W Davis; Yongmei Zhao; Anupama Joseph; Traci Kruthaupt; Nickki Ottaway; Dhiraj Kabra; Kirk M Habegger; Stephen C Benoit; Martin Bidlingmaier; Michael O Thorner; Diego Perez-Tilve; Matthias H Tschöp; Paul T Pfluger
Journal:  PLoS One       Date:  2012-02-21       Impact factor: 3.240
View more
  30 in total

1.  Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa.

Authors:  Katherine N Bachmann; Melanie Schorr; Alexander G Bruno; Miriam A Bredella; Elizabeth A Lawson; Corey M Gill; Vibha Singhal; Erinne Meenaghan; Anu V Gerweck; Meghan Slattery; Kamryn T Eddy; Seda Ebrahimi; Stuart L Koman; James M Greenblatt; Robert J Keane; Thomas Weigel; Madhusmita Misra; Mary L Bouxsein; Anne Klibanski; Karen K Miller
Journal:  J Clin Endocrinol Metab       Date:  2017-01-01       Impact factor: 5.958

Review 2.  Gut Microbiota and IGF-1.

Authors:  Jing Yan; Julia F Charles
Journal:  Calcif Tissue Int       Date:  2018-01-23       Impact factor: 4.333

Review 3.  Bone Marrow Adiposity: Basic and Clinical Implications.

Authors:  Zachary L Sebo; Elizabeth Rendina-Ruedy; Gene P Ables; Dieter M Lindskog; Matthew S Rodeheffer; Pouneh K Fazeli; Mark C Horowitz
Journal:  Endocr Rev       Date:  2019-10-01       Impact factor: 19.871

4.  Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma.

Authors:  Kevin C Corbit; Camella G Wilson; Dylan Lowe; Jennifer L Tran; Nicholas B Vera; Michelle Clasquin; Aras N Mattis; Ethan J Weiss
Journal:  JCI Insight       Date:  2019-08-08

5.  Characteristics of Gut Microbiome and Its Metabolites, Short-Chain Fatty Acids, in Children With Idiopathic Short Stature.

Authors:  Lin Li; Lifen Chen; Yuanyan Yang; Junqi Wang; Li Guo; Jingjing An; Xiaoyu Ma; Wenli Lu; Yuan Xiao; Xinqiong Wang; Zhiya Dong
Journal:  Front Endocrinol (Lausanne)       Date:  2022-06-10       Impact factor: 6.055

6.  Roles of leptin in initiation of acquired growth hormone resistance and control of metabolism in rainbow trout.

Authors:  Ningping Gong; Jakob Lundin; Daniel Morgenroth; Mark A Sheridan; Erik Sandblom; Björn Thrandur Björnsson
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2022-03-16       Impact factor: 3.210

Review 7.  The Path Towards Progress: A Critical Review to Advance the Science of the Female and Male Athlete Triad and Relative Energy Deficiency in Sport.

Authors:  Mary Jane De Souza; Nicole C A Strock; Emily A Ricker; Kristen J Koltun; Michelle Barrack; Elizabeth Joy; Aurelia Nattiv; Mark Hutchinson; Madhusmita Misra; Nancy I Williams
Journal:  Sports Med       Date:  2021-10-19       Impact factor: 11.928

8.  Selective protein depletion impairs bone growth and causes liver fatty infiltration in female rats: prevention by Spirulina alga.

Authors:  C Fournier; R Rizzoli; K Bouzakri; P Ammann
Journal:  Osteoporos Int       Date:  2016-06-25       Impact factor: 4.507

9.  Prepartum and Postpartum Feed Restrictions Affect Blood Metabolites and Hormones Reducing Colostrum and Milk Yields in Fat-Tailed Dairy Sheep.

Authors:  Mousa Zarrin; Meysam Sanginabadi; Mahrokh Nouri; Amir Ahmadpour; Lorenzo E Hernández-Castellano
Journal:  Animals (Basel)       Date:  2021-04-27       Impact factor: 2.752

10.  Caloric restriction induces anabolic resistance to resistance exercise.

Authors:  Chaise Murphy; Karsten Koehler
Journal:  Eur J Appl Physiol       Date:  2020-03-31       Impact factor: 3.078
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.