Literature DB >> 24361632

Beyond prevention of mother-to-child transmission: keeping HIV-exposed and HIV-positive children healthy and alive.

Scott E Kellerman1, Saeed Ahmed, Theresa Feeley-Summerl, Jonathan Jay, Maria Kim, B Ryan Phelps, Nandita Sugandhi, Erik Schouten, Mike Tolle, Fatima Tsiouris.   

Abstract

In 2011, Joint United Nations Programme on HIV/AIDS announced a plan to eliminate new HIV infections among children by 2015. This increased focus on the elimination of maternal to child transmission (MTCT) is most welcome but is insufficient, as access to prevention of MTCT (PMTCT) programming is neither uniform nor universal. A new and more expansive agenda must be articulated to ensure that those infants and children who will never feel the impact of the current elimination agenda are reached and linked to appropriate care and treatment. This agenda must addresses challenges around both reducing vertical transmission through PMTCT and ensuring access to appropriate HIV testing, care, and treatment for all affected children who were never able to access PMTCT programming. Option B+, or universal test and treat for HIV-infected pregnant women is an excellent start, but it may be time to rethink our current approaches to delivering PMTCT services. New strategies will reduce vertical transmission to less than 1% for those mother-infant pairs who can access them allowing for the contemplation of not just PMTCT, but actual elimination of MTCT. But expanded thinking is needed to ensure elimination of pediatric HIV.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 24361632      PMCID: PMC4087192          DOI: 10.1097/QAD.0000000000000107

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  39 in total

1.  Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model.

Authors:  Reuben M Granich; Charles F Gilks; Christopher Dye; Kevin M De Cock; Brian G Williams
Journal:  Lancet       Date:  2008-11-27       Impact factor: 79.321

2.  Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (hiv network for prevention trials 012 study).

Authors:  S H Eshleman; G Becker-Pergola; M Deseyve; L A Guay; M Mracna; T Fleming; S Cunningham; P Musoke; F Mmiro; J B Jackson
Journal:  J Infect Dis       Date:  2001-08-13       Impact factor: 5.226

3.  Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis. WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality.

Authors: 
Journal:  Lancet       Date:  2000-02-05       Impact factor: 79.321

4.  Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial.

Authors:  L A Guay; P Musoke; T Fleming; D Bagenda; M Allen; C Nakabiito; J Sherman; P Bakaki; C Ducar; M Deseyve; L Emel; M Mirochnick; M G Fowler; L Mofenson; P Miotti; K Dransfield; D Bray; F Mmiro; J B Jackson
Journal:  Lancet       Date:  1999-09-04       Impact factor: 79.321

5.  Embracing a family-centred response to the HIV/AIDS epidemic for the elimination of pediatric AIDS.

Authors:  V DeGennaro; P Zeitz
Journal:  Glob Public Health       Date:  2009

6.  A package of primary health care services for comprehensive family-centred HIV/AIDS care and treatment programs in low-income settings.

Authors:  Michael A Tolle
Journal:  Trop Med Int Health       Date:  2009-04-13       Impact factor: 2.622

7.  Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission.

Authors:  Newton I Kumwenda; Donald R Hoover; Lynne M Mofenson; Michael C Thigpen; George Kafulafula; Qing Li; Linda Mipando; Kondwani Nkanaunena; Tsedal Mebrahtu; Marc Bulterys; Mary Glenn Fowler; Taha E Taha
Journal:  N Engl J Med       Date:  2008-06-04       Impact factor: 91.245

8.  Prevention of mother-to-child transmission of HIV-1 through breastfeeding by treating mothers with triple antiretroviral therapy in Dar es Salaam, Tanzania: the Mitra Plus study.

Authors:  Charles Kilewo; Katarina Karlsson; Matilda Ngarina; Augustine Massawe; Eligius Lyamuya; Andrew Swai; Rosina Lipyoga; Fred Mhalu; Gunnel Biberfeld
Journal:  J Acquir Immune Defic Syndr       Date:  2009-11-01       Impact factor: 3.731

9.  Early antiretroviral therapy and mortality among HIV-infected infants.

Authors:  Avy Violari; Mark F Cotton; Diana M Gibb; Abdel G Babiker; Jan Steyn; Shabir A Madhi; Patrick Jean-Philippe; James A McIntyre
Journal:  N Engl J Med       Date:  2008-11-20       Impact factor: 91.245

Review 10.  Diagnosis of HIV-1 infection in children younger than 18 months in the United States.

Authors:  Jennifer S Read
Journal:  Pediatrics       Date:  2007-12       Impact factor: 7.124

View more
  19 in total

1.  Implementation and Operational Research: Active Referral of Children of HIV-Positive Adults Reveals High Prevalence of Undiagnosed HIV.

Authors:  Anjuli D Wagner; Cyrus Mugo; Irene N Njuguna; Elizabeth Maleche-Obimbo; Kenneth Sherr; Irene W Inwani; James P Hughes; Dalton C Wamalwa; Grace C John-Stewart; Jennifer A Slyker
Journal:  J Acquir Immune Defic Syndr       Date:  2016-12-15       Impact factor: 3.731

2.  National estimates and risk factors associated with early mother-to-child transmission of HIV after implementation of option B+: a cross-sectional analysis.

Authors:  Beth A Tippett Barr; Monique van Lettow; Joep J van Oosterhout; Megan Landes; Ray W Shiraishi; Ermias Amene; Erik Schouten; Nellie Wadonda-Kabondo; Sundeep Gupta; Andrew F Auld; Thokozani Kalua; Andreas Jahn
Journal:  Lancet HIV       Date:  2018-11-19       Impact factor: 12.767

3.  HIV-Infected Ugandan Women on Antiretroviral Therapy Maintain HIV-1 RNA Suppression Across Periconception, Pregnancy, and Postpartum Periods.

Authors:  Lynn T Matthews; Heather B Ribaudo; Angela Kaida; Kara Bennett; Nicholas Musinguzi; Mark J Siedner; Jerome Kabakyenga; Peter W Hunt; Jeffrey N Martin; Yap Boum; Jessica E Haberer; David R Bangsberg
Journal:  J Acquir Immune Defic Syndr       Date:  2016-04-01       Impact factor: 3.731

Review 4.  Addressing Common Mental Health Disorders Among Incarcerated People Living with HIV: Insights from Implementation Science for Service Integration and Delivery.

Authors:  Helene J Smith; Stephanie M Topp; Christopher J Hoffmann; Thulani Ndlovu; Salome Charalambous; Laura Murray; Jeremy Kane; Izukanji Sikazwe; Monde Muyoyeta; Michael E Herce
Journal:  Curr HIV/AIDS Rep       Date:  2020-10       Impact factor: 5.071

5.  The effects of caregiver and household HIV on child development: a community-based longitudinal study of young children.

Authors:  L Sherr; S Skeen; I S Hensels; M Tomlinson; A Macedo
Journal:  Child Care Health Dev       Date:  2016-08-11       Impact factor: 2.508

6.  Women and Children First: The Impact of Sexually Transmitted Infections on Maternal and Child Health.

Authors:  Consuelo Beck Sagué; Carolyn Black; Stephen A Morse; George Schmid
Journal:  J Sex Transm Dis       Date:  2014-02-18

7.  Maternal and health care workers' perceptions of the effects of exclusive breastfeeding by HIV positive mothers on maternal and infant health in Blantyre, Malawi.

Authors:  Ursula K Kafulafula; Mary K Hutchinson; Susan Gennaro; Sally Guttmacher
Journal:  BMC Pregnancy Childbirth       Date:  2014-07-25       Impact factor: 3.007

8.  Supporting Option B+ scale up and strengthening the prevention of mother-to-child transmission cascade in central Malawi: results from a serial cross-sectional study.

Authors:  Michael E Herce; Tiwonge Mtande; Frank Chimbwandira; Innocent Mofolo; Christine K Chingondole; Nora E Rosenberg; Kathy E Lancaster; Esmie Kamanga; Jacqueline Chinkonde; Wiza Kumwenda; Gerald Tegha; Mina C Hosseinipour; Irving F Hoffman; Francis E Martinson; Eva Stein; Charles M van der Horst
Journal:  BMC Infect Dis       Date:  2015-08-12       Impact factor: 3.090

9.  Brief Report: Impact of Option B+ on the Infant PMTCT Cascade in Lilongwe, Malawi.

Authors:  Maria H Kim; Saeed Ahmed; Mina C Hosseinipour; Xiaoying Yu; Chi Nguyen; Frank Chimbwandira; Mary E Paul; Peter N Kazembe; Elaine J Abrams
Journal:  J Acquir Immune Defic Syndr       Date:  2015-09-01       Impact factor: 3.731

10.  Point-of-care CD4 testing to inform selection of antiretroviral medications in south african antenatal clinics: a cost-effectiveness analysis.

Authors:  Andrea L Ciaranello; Landon Myer; Kathleen Kelly; Sarah Christensen; Kristen Daskilewicz; Katie Doherty; Linda-Gail Bekker; Taige Hou; Robin Wood; Jordan A Francke; Kara Wools-Kaloustian; Kenneth A Freedberg; Rochelle P Walensky
Journal:  PLoS One       Date:  2015-03-10       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.