Davy Vancampfort1, Michel Probst2, Brendon Stubbs3, Andrew Soundy4, Amber De Herdt5, Marc De Hert5. 1. University Psychiatric Centre KU Leuven, Kortenberg, KU Leuven Departement of Neurosciences, B-3070Kortenberg, Belgium; KU Leuven Department of Rehabilitation Sciences, B-3001Leuven, Belgium. Electronic address: Davy.Vancampfort@uc-kortenberg.be. 2. University Psychiatric Centre KU Leuven, Kortenberg, KU Leuven Departement of Neurosciences, B-3070Kortenberg, Belgium; KU Leuven Department of Rehabilitation Sciences, B-3001Leuven, Belgium. 3. School of Health and Social Care, University of Greenwich,Eltham, LondonSE9 2UG, UK. 4. Department of Physiotherapy, University of Birmingham, Birmingham, B15 2TT, UK. 5. KU Leuven Department of Rehabilitation Sciences, B-3001Leuven, Belgium.
Abstract
OBJECTIVE: This cross-sectional study considered whether variability in respiratory functioning could explain the variability in walking ability of individuals with schizophrenia taking into account variability in body mass index (BMI), lifestyle factors, psychiatric symptoms, antipsychotic medication use and muscular fitness. METHOD: Eighty patients with schizophrenia and 40 age-, gender- and BMI-matched controls underwent a spirometry and the 6-min walk test (6 MWT) and completed the International Physical Activity Questionnaire. Patients were additionally screened for psychiatric symptoms. RESULTS: Compared to health controls, patients with schizophrenia achieved a lower distance on the 6 MWT (583.6 ± 109.7 m versus 710.6 ± 108.4 m, P<.001) and had a lower forced vital capacity (3.7 ± 1.1 L versus 4.3 ± 0.9 L, P<.001) and forced expiratory volume in 1 s (FEV1) (3.0 ± 1.0 L versus 3.6 ± 0.7 L, P<.001). In multiple regression analysis, 68.1% of the variance in walking distance was explained by FEV1, BMI, muscular fitness and total energy expenditure. CONCLUSION: The respiratory health of patients with schizophrenia should be of concern for clinicians. In addition, future research interventions should seek to investigate the impact of an impaired respiratory health upon individuals with schizophrenia.
OBJECTIVE: This cross-sectional study considered whether variability in respiratory functioning could explain the variability in walking ability of individuals with schizophrenia taking into account variability in body mass index (BMI), lifestyle factors, psychiatric symptoms, antipsychotic medication use and muscular fitness. METHOD: Eighty patients with schizophrenia and 40 age-, gender- and BMI-matched controls underwent a spirometry and the 6-min walk test (6 MWT) and completed the International Physical Activity Questionnaire. Patients were additionally screened for psychiatric symptoms. RESULTS: Compared to health controls, patients with schizophrenia achieved a lower distance on the 6 MWT (583.6 ± 109.7 m versus 710.6 ± 108.4 m, P<.001) and had a lower forced vital capacity (3.7 ± 1.1 L versus 4.3 ± 0.9 L, P<.001) and forced expiratory volume in 1 s (FEV1) (3.0 ± 1.0 L versus 3.6 ± 0.7 L, P<.001). In multiple regression analysis, 68.1% of the variance in walking distance was explained by FEV1, BMI, muscular fitness and total energy expenditure. CONCLUSION: The respiratory health of patients with schizophrenia should be of concern for clinicians. In addition, future research interventions should seek to investigate the impact of an impaired respiratory health upon individuals with schizophrenia.
Authors: M J Jaen-Moreno; N Feu; G I Del Pozo; C Gómez; L Carrión; G M Chauca; I Guler; F J Montiel; M D Sánchez; J A Alcalá; L Gutierrez-Rojas; V Molina; J Bobes; V Balanzá-Martínez; C Ruiz-Rull; F Sarramea Journal: Eur Psychiatry Date: 2021-02-26 Impact factor: 5.361