Literature DB >> 2436051

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase.

P M Colman, W G Laver, J N Varghese, A T Baker, P A Tulloch, G M Air, R G Webster.   

Abstract

The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen-antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction therefore has some of the character of a handshake.

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Year:  1987        PMID: 2436051     DOI: 10.1038/326358a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  92 in total

1.  Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state.

Authors:  M Horiuchi; B Caughey
Journal:  EMBO J       Date:  1999-06-15       Impact factor: 11.598

2.  Role of constraint in catalysis and high-affinity binding by proteins.

Authors:  Donald G Vanselow
Journal:  Biophys J       Date:  2002-05       Impact factor: 4.033

3.  The C-terminal portion of RAG2 protects against transposition in vitro.

Authors:  Sheryl K Elkin; Adam G Matthews; Marjorie A Oettinger
Journal:  EMBO J       Date:  2003-04-15       Impact factor: 11.598

Review 4.  Insights into neutralization of animal viruses gained from study of influenza virus.

Authors:  M C Outlaw; N J Dimmock
Journal:  Epidemiol Infect       Date:  1991-04       Impact factor: 2.451

5.  Modeling the three-dimensional structures of an unbound single-chain variable fragment (scFv) and its hypothetical complex with a Corynespora cassiicola toxin, cassiicolin.

Authors:  Adeel Malik; Ahmad Firoz; Vivekanand Jha; Elumalai Sunderasan; Shandar Ahmad
Journal:  J Mol Model       Date:  2010-03-16       Impact factor: 1.810

6.  Three antibody molecules can bind simultaneously to each monomer of the tetramer of influenza virus neuraminidase and the trimer of influenza virus hemagglutinin.

Authors:  D C Jackson; B S Crabb; P Poumbourios; W R Tulip; W G Laver
Journal:  Arch Virol       Date:  1991       Impact factor: 2.574

7.  Preparation and crystallization of a human immunodeficiency virus p24-Fab complex.

Authors:  A J Prongay; T J Smith; M G Rossmann; L S Ehrlich; C A Carter; J McClure
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

8.  Three quaternary structures for a single protein.

Authors:  D B Huang; C F Ainsworth; F J Stevens; M Schiffer
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

9.  A novel function of the herpes simplex virus type 1 Fc receptor: participation in bipolar bridging of antiviral immunoglobulin G.

Authors:  I Frank; H M Friedman
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

10.  Conformational heterogeneity in antibody-protein antigen recognition: implications for high affinity protein complex formation.

Authors:  Philip W Addis; Catherine J Hall; Shaun Bruton; Vaclav Veverka; Ian C Wilkinson; Frederick W Muskett; Philip S Renshaw; Christine E Prosser; Bruce Carrington; Alastair D G Lawson; Robert Griffin; Richard J Taylor; Lorna C Waters; Alistair J Henry; Mark D Carr
Journal:  J Biol Chem       Date:  2014-01-16       Impact factor: 5.157

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