Literature DB >> 24360270

Probing DNA by 2-OG-dependent dioxygenase.

Chi-Lin Tsai1, John A Tainer2.   

Abstract

TET-mediated 5-methyl cytosine (5mC) oxidation acts in epigenetic regulation, stem cell development, and cancer. Hu et al. now determine the crystal structure of the TET2 catalytic domain bound to DNA, shedding light on 5mC-DNA substrate recognition and the catalytic mechanism of 5mC oxidation.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24360270      PMCID： PMC3916139          DOI： 10.1016/j.cell.2013.12.002

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  8 in total

1.  DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation.

Authors:  Sebastian Dango; Nima Mosammaparast; Mathew E Sowa; Li-Jun Xiong; Feizhen Wu; Keyjung Park; Mark Rubin; Steve Gygi; J Wade Harper; Yang Shi
Journal:  Mol Cell       Date:  2011-11-04       Impact factor: 17.970

Review 2.  TET enzymes, TDG and the dynamics of DNA demethylation.

Authors:  Rahul M Kohli; Yi Zhang
Journal:  Nature       Date:  2013-10-24       Impact factor: 49.962

3.  Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.

Authors:  Ottar Sundheim; Cathrine B Vågbø; Magnar Bjørås; Mirta M L Sousa; Vivi Talstad; Per A Aas; Finn Drabløs; Hans E Krokan; John A Tainer; Geir Slupphaug
Journal:  EMBO J       Date:  2006-07-06       Impact factor: 11.598

4.  Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.

Authors:  Cai-Guang Yang; Chengqi Yi; Erica M Duguid; Christopher T Sullivan; Xing Jian; Phoebe A Rice; Chuan He
Journal:  Nature       Date:  2008-04-24       Impact factor: 49.962

5.  Mutation in TET2 in myeloid cancers.

Authors:  François Delhommeau; Sabrina Dupont; Véronique Della Valle; Chloé James; Severine Trannoy; Aline Massé; Olivier Kosmider; Jean-Pierre Le Couedic; Fabienne Robert; Antonio Alberdi; Yann Lécluse; Isabelle Plo; François J Dreyfus; Christophe Marzac; Nicole Casadevall; Catherine Lacombe; Serge P Romana; Philippe Dessen; Jean Soulier; Franck Viguié; Michaela Fontenay; William Vainchenker; Olivier A Bernard
Journal:  N Engl J Med       Date:  2009-05-28       Impact factor: 91.245

6.  Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Authors:  Myunggon Ko; Jungeun An; Hozefa S Bandukwala; Lukas Chavez; Tarmo Aijö; William A Pastor; Matthew F Segal; Huiming Li; Kian Peng Koh; Harri Lähdesmäki; Patrick G Hogan; L Aravind; Anjana Rao
Journal:  Nature       Date:  2013-04-07       Impact factor: 49.962

7.  Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-π interactions.

Authors:  Oliver J Wilkinson; Vitaly Latypov; Julie L Tubbs; Christopher L Millington; Rihito Morita; Hannah Blackburn; Andrew Marriott; Gail McGown; Mary Thorncroft; Amanda J Watson; Bernard A Connolly; Jane A Grasby; Ryoji Masui; Christopher A Hunter; John A Tainer; Geoffrey P Margison; David M Williams
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-29       Impact factor: 11.205

8.  Duplex interrogation by a direct DNA repair protein in search of base damage.

Authors:  Chengqi Yi; Baoen Chen; Bo Qi; Wen Zhang; Guifang Jia; Liang Zhang; Charles J Li; Aaron R Dinner; Cai-Guang Yang; Chuan He
Journal:  Nat Struct Mol Biol       Date:  2012-06-03       Impact factor: 15.369
  8 in total
  2 in total

1.  Comparison of DNA and RNA substrate effects on TET2 structure.

Authors:  Emmett M Leddin; G Andrés Cisneros
Journal:  Adv Protein Chem Struct Biol       Date:  2019-06-11       Impact factor: 3.507

Review 2.  TET-dioxygenase deficiency in oncogenesis and its targeting for tumor-selective therapeutics.

Authors:  Yihong Guan; Metis Hasipek; Anand D Tiwari; Jaroslaw P Maciejewski; Babal K Jha
Journal:  Semin Hematol       Date:  2020-12-28       Impact factor: 3.851
  2 in total

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