Literature DB >> 24359934

Application of a non-amplification-based technology to detect invasive fungal pathogens.

Joe L Hsu1, Jon Binkley2, Karl V Clemons3, David A Stevens3, Mark R Nicolls4, Mark Holodniy5.   

Abstract

Current diagnostic techniques for fungal diseases could be improved with respect to sensitivity, specificity, and timeliness. To address this clinical need, we adapted a non-amplification-based nucleic acid detection technology to identify fungal pathogens. We demonstrate a high-specificity, detection sensitivity, reproducibility, and multiplex capacity for detecting fungal strains.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Aspergillus; Candida; Diagnosis; Invasive fungal disease; nCounter analysis system

Mesh：

Year:  2013        PMID： 24359934      PMCID： PMC4583138          DOI： 10.1016/j.diagmicrobio.2013.11.013

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  7 in total

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Review 3.  Diagnosing invasive fungal disease in critically ill patients.

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Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-02       Impact factor: 11.205

5.  Correlation of restriction fragment length polymorphism genotyping with internal transcribed spacer sequence, randomly amplified polymorphic DNA and multilocus sequence groupings for Candida parapsilosis.

Authors:  Eveline C van Asbeck; Karl V Clemons; Angela N Markham; David A Stevens
Journal:  Mycoses       Date:  2009-01-24       Impact factor: 4.377

6.  The Aspergillus Genome Database (AspGD): recent developments in comprehensive multispecies curation, comparative genomics and community resources.

Authors:  Martha B Arnaud; Gustavo C Cerqueira; Diane O Inglis; Marek S Skrzypek; Jonathan Binkley; Marcus C Chibucos; Jonathan Crabtree; Clinton Howarth; Joshua Orvis; Prachi Shah; Farrell Wymore; Gail Binkley; Stuart R Miyasato; Matt Simison; Gavin Sherlock; Jennifer R Wortman
Journal:  Nucleic Acids Res       Date:  2011-11-12       Impact factor: 16.971

7.  Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile.

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Journal:  Infect Agent Cancer       Date:  2012-08-28       Impact factor: 2.965
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2.  Targeted Treatment for Bacterial Infections: Prospects for Pathogen-Specific Antibiotics Coupled with Rapid Diagnostics.

Authors:  Tucker Maxson; Douglas A Mitchell
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  2 in total

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