Literature DB >> 24357709

A new view of integrin αIIbβ3 bound to membrane.

Jun Qin1, Edward F Plow.   

Abstract

In this issue of Blood, Choi et al report a 3-dimensional (3D) reconstruction model of integrin aIIbb3 in its latent state which challenges the existing paradigm and provides new insights into the mechanism of integrin activation.

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Year:  2013        PMID： 24357709      PMCID： PMC3868923          DOI： 10.1182/blood-2013-10-534149

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  10 in total

1.  Crystal structure of the extracellular segment of integrin alpha Vbeta3.

Authors:  J P Xiong; T Stehle; B Diefenbach; R Zhang; R Dunker; D L Scott; A Joachimiak; S L Goodman; M A Arnaout
Journal:  Science       Date:  2001-09-06       Impact factor: 47.728

2.  Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography.

Authors:  Brian D Adair; Mark Yeager
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-18       Impact factor: 11.205

3.  The molecular basis of filamin binding to integrins and competition with talin.

Authors:  Tiila Kiema; Yatish Lad; Pengju Jiang; Camilla L Oxley; Massimiliano Baldassarre; Kate L Wegener; Iain D Campbell; Jari Ylänne; David A Calderwood
Journal:  Mol Cell       Date:  2006-02-03       Impact factor: 17.970

Review 4.  Integrins: bidirectional, allosteric signaling machines.

Authors:  Richard O Hynes
Journal:  Cell       Date:  2002-09-20       Impact factor: 41.582

5.  The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling.

Authors:  Tong-Lay Lau; Chungho Kim; Mark H Ginsberg; Tobias S Ulmer
Journal:  EMBO J       Date:  2009-03-12       Impact factor: 11.598

Review 6.  Integrin inactivators: balancing cellular functions in vitro and in vivo.

Authors:  Daniel Bouvard; Jeroen Pouwels; Nicola De Franceschi; Johanna Ivaska
Journal:  Nat Rev Mol Cell Biol       Date:  2013-05-30       Impact factor: 94.444

7.  Three-dimensional reconstruction of intact human integrin αIIbβ3: new implications for activation-dependent ligand binding.

Authors:  Won-Seok Choi; William J Rice; David L Stokes; Barry S Coller
Journal:  Blood       Date:  2013-10-17       Impact factor: 22.113

8.  Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.

Authors:  Jun Yang; Yan-Qing Ma; Richard C Page; Saurav Misra; Edward F Plow; Jun Qin
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-01       Impact factor: 11.205

9.  NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.

Authors:  Douglas G Metcalf; David T Moore; Yibing Wu; Joseph M Kielec; Kathleen Molnar; Kathleen G Valentine; A Joshua Wand; Joel S Bennett; William F DeGrado
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-14       Impact factor: 11.205

Review 10.  Integrin structure, activation, and interactions.

Authors:  Iain D Campbell; Martin J Humphries
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-03-01       Impact factor: 10.005
  10 in total

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