| Literature DB >> 24356737 |
Pía Villarroel H1, Miguel Arredondo O1, Manuel Olivares G1.
Abstract
Recent evidence suggests that obesity-related inflammation may play a central role in hepcidin regulation. Hepcidin is a key regulator ofiron homeostasis and has now been suggested as a central mediator ofiron metabolism disorders involved in the pathogenesis of anemia of chronic disease. In this review, we focus on subclinical inflammation in obesity and its effect on hepcidin levels, as the most plausible explanation for the relationship between anemia of chronic disease and obesity.Entities:
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Year: 2013 PMID: 24356737 DOI: 10.4067/S0034-98872013000700008
Source DB: PubMed Journal: Rev Med Chil ISSN: 0034-9887 Impact factor: 0.553