Literature DB >> 2435666

Rejoining of double strand breaks in normal human and ataxia-telangiectasia fibroblasts after exposure to 60Co gamma-rays, 241Am alpha-particles or bleomycin.

T M Coquerelle, K F Weibezahn, C Lücke-Huhle.   

Abstract

The rejoining of DNA double strand breaks (dsb) induced by 60Co gamma-rays, 241Am alpha-particles or bleomycin was measured by neutral filter elution. In agreement with their colony-forming ability, ataxia-telangiectasia cells (AT2BE) and normal fibroblasts exhibited similar dsb rejoining capacity following alpha-irradiation, but showed marked differences in the rejoining kinetics of dsb induced by gamma-rays or bleomycin.

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Year:  1987        PMID： 2435666     DOI： 10.1080/09553008714550711

Source DB:  PubMed          Journal:  Int J Radiat Biol Relat Stud Phys Chem Med        ISSN： 0020-7616


  6 in total

Review 1.  Cell inactivation by heavy charged particles.

Authors:  E A Blakely
Journal:  Radiat Environ Biophys       Date:  1992       Impact factor: 1.925

Review 2.  Induction, repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells.

Authors:  M Frankenberg-Schwager
Journal:  Radiat Environ Biophys       Date:  1990       Impact factor: 1.925

3.  Cell cycle dependent DNA break increase in ataxia telangiectasia lymphoblasts after radiation exposure.

Authors:  B Humar; H Müller; R J Scott
Journal:  Mol Pathol       Date:  2001-10

4.  Similarities between human ataxia fibroblasts and murine SCID cells: high sensitivity to gamma rays and high frequency of methotrexate-induced DHFR gene amplification, but normal radiosensitivity to densely ionizing alpha particles.

Authors:  C Lücke-Huhle
Journal:  Radiat Environ Biophys       Date:  1994       Impact factor: 1.925

5.  Heavy ion-induced DNA double-strand breaks with yeast as a model system.

Authors:  S Ikpeme; M Löbrich; T Akpa; E Schneider; J Kiefer
Journal:  Radiat Environ Biophys       Date:  1995-06       Impact factor: 1.925

6.  A DNA repair defect in a radiation-sensitive clone of a human bladder carcinoma cell line.

Authors:  S N Powell; S J Whitaker; S M Edwards; T J McMillan
Journal:  Br J Cancer       Date:  1992-06       Impact factor: 7.640
  6 in total

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