Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Meiosis: cohesin's hidden role in the checkpoint revealed.

Literature DB >> 24355789

Meiosis: cohesin's hidden role in the checkpoint revealed.

Abstract

The spindle assembly checkpoint prevents aneuploidy by ensuring that chromosomes are properly distributed during cell division. A new study shows that the integrity of the checkpoint response depends on centromeric cohesin in mammalian oocytes.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2013 PMID： 24355789 PMCID： PMC4210767 DOI： 10.1016/j.cub.2013.10.076

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

Keyword Cloud
References

20 in total

1. Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes.

Authors: Liming Gui; Hayden Homer
Journal: Development Date: 2012-04-18 Impact factor: 6.868

2. Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension.

Authors: Simon I R Lane; Yan Yun; Keith T Jones
Journal: Development Date: 2012-04-18 Impact factor: 6.868

3. Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errors.

Authors: So Iha Nagaoka; Craig A Hodges; David F Albertini; Patricia Ann Hunt
Journal: Curr Biol Date: 2011-04-14 Impact factor: 10.834

4. Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes.

Authors: Kikuë Tachibana-Konwalski; Jonathan Godwin; Louise van der Weyden; Lysie Champion; Nobuaki R Kudo; David J Adams; Kim Nasmyth
Journal: Genes Dev Date: 2010-10-22 Impact factor: 11.361

5. Age-related meiotic segregation errors in mammalian oocytes are preceded by depletion of cohesin and Sgo2.

Authors: Lisa Martine Lister; Anna Kouznetsova; Louise Ann Hyslop; Dimitrios Kalleas; Sarah Louise Pace; Jaclyn Catharina Barel; Abinaya Nathan; Vasileios Floros; Caroline Adelfalk; Yoshinori Watanabe; Rolf Jessberger; Thomas B Kirkwood; Christer Höög; Mary Herbert
Journal: Curr Biol Date: 2010-09-14 Impact factor: 10.834

Meiosis: cohesin's hidden role in the checkpoint revealed.

1. Spindle assembly checkpoint signalling is uncoupled from chromosomal position in mouse oocytes.

2. Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension.

3. Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errors.

4. Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes.

5. Age-related meiotic segregation errors in mammalian oocytes are preceded by depletion of cohesin and Sgo2.

6. Oocyte cohesin expression restricted to predictyate stages provides full fertility and prevents aneuploidy.

7. Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes.

8. Complete kinetochore tracking reveals error-prone homologous chromosome biorientation in mammalian oocytes.

9. Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes.

10. The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice.