Literature DB >> 24355178

CT brain findings in a patient with elevated brain cesium levels.

Simon R Khangure1, Eric S Williams, Christopher J Welman.   

Abstract

We describe the CT findings in the brain of a woman with pathologically proven elevated levels of blood and tissue cesium. The 42-year-old woman had been receiving cesium chloride as a non-mainstream treatment for metastatic breast carcinoma. She presented to hospital following a seizure, and died 48 hours after admission. A brain CT performed on hospital admission showed a diffuse increase in attenuation of brain parenchyma. Autopsy revealed elevated levels of cesium in blood and solid organs including the brain. We hypothesize that the imaging findings are attributable to the abnormally elevated level of brain cesium at the time of the CT scan. To our knowledge, this is the first reported case of this imaging finding.

Entities:  

Keywords:  brain; cesium; computed tomography

Mesh:

Substances:

Year:  2013        PMID: 24355178      PMCID: PMC4202877          DOI: 10.1177/197140091302600602

Source DB:  PubMed          Journal:  Neuroradiol J        ISSN: 1971-4009


  9 in total

1.  Cesium-induced torsades de pointes.

Authors:  Arnold Pinter; Paul Dorian; David Newman
Journal:  N Engl J Med       Date:  2002-01-31       Impact factor: 91.245

2.  Cesium chloride-induced torsades de pointes.

Authors:  Matthew Wiens; Wendy Gordon; Daisy Baulcomb; Andre Mattman; Tom Mock; Robert Brown
Journal:  Can J Cardiol       Date:  2009-09       Impact factor: 5.223

3.  Computed tomographic analysis of brain morphometrics in 30 healthy men, aged 21 to 81 years.

Authors:  M Schwartz; H Creasey; C L Grady; J M DeLeo; H A Frederickson; N R Cutler; S I Rapoport
Journal:  Ann Neurol       Date:  1985-02       Impact factor: 10.422

4.  Brain density and cerebrospinal fluid space size: CT of normal volunteers.

Authors:  L A Cala; G W Thickbroom; J L Black; D W Collins; F L Mastaglia
Journal:  AJNR Am J Neuroradiol       Date:  1981 Jan-Feb       Impact factor: 3.825

Review 5.  Clinical effects of cesium intake.

Authors:  Petr Melnikov; Lourdes Zélia Zanoni
Journal:  Biol Trace Elem Res       Date:  2009-08-05       Impact factor: 3.738

6.  The high pH therapy for cancer tests on mice and humans.

Authors:  A K Brewer
Journal:  Pharmacol Biochem Behav       Date:  1984       Impact factor: 3.533

7.  Life-threatening Torsades de Pointes resulting from "natural" cancer treatment.

Authors:  C K Chan; M H M Chan; M L Tse; I H S Chan; R C K Cheung; C W K Lam; F L Lau
Journal:  Clin Toxicol (Phila)       Date:  2009-07       Impact factor: 4.467

Review 8.  Cesium-induced QT-interval prolongation in an adolescent.

Authors:  Catherine E O'Brien; Nada Harik; Laura P James; Paul M Seib; Cindy D Stowe
Journal:  Pharmacotherapy       Date:  2008-08       Impact factor: 4.705

9.  Blood and tissue concentration of cesium after exposure to cesium chloride: a report of two cases.

Authors:  José A Centeno; Joseph P Pestaner; Bennet I Omalu; Norca L Torres; Frances Field; Glenn Wagner; Florabel G Mullick
Journal:  Biol Trace Elem Res       Date:  2003-08       Impact factor: 3.738

  9 in total
  1 in total

1.  Cesium-associated hypokalemia successfully treated with amiloride.

Authors:  Sarah Horn; Elliot Naidus; Seth L Alper; John Danziger
Journal:  Clin Kidney J       Date:  2015-03-31
  1 in total

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