Toxicological effects of emissions from diesel engines.

The 29 papers at this international symposium demonstrate the success of the past decade's research on diesel exhaust emissions. The observations made in different countries which have utilized biological systems ranging from macromolecules to cells and tissues to populations of animals and people are highly complementary. The findings presented here, combined with estimates of diesel exhaust exposure, provide the basis for development of qualitative and, perhaps semi-quantitative, estimates of cancer risk from exposure to diesel exhaust. In addition, the research reported provides valuable insight into the mechanisms by which inhalation of complex mixtures may cause lung cancer.