Literature DB >> 24354245

[Autophagy and immune response].

Maria Johanna Peña-Sanoja1, Juan Bautista De Sanctis1.   

Abstract

Autophagy is a complex process in which cell homeostasis of proteins, organelles, exocitic and endocitic vacuoles are controlled. There is a direct link between autophagy and cell death with antigen processing, generation of inflammatory response and immune response. In different diseases, deficiencies in autophagy have been reported. It has been proposed that in early stages of cancer, autophagy is capable of inducing cell death; however, in agresive tumors and metastasis, the process is responsible for pharmacologic resistance and tumor survival. More research has to be done in order to allow us to understand the process and generate therapeutic options in different pathologies important for the human being.

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Year:  2013        PMID: 24354245

Source DB:  PubMed          Journal:  Invest Clin        ISSN: 0535-5133            Impact factor:   0.683


  2 in total

1.  Network analysis reveals crosstalk between autophagy genes and disease genes.

Authors:  Ji-Ye Wang; Wei-Xuan Yao; Yun Wang; Yi-Lei Fan; Jian-Bing Wu
Journal:  Sci Rep       Date:  2017-03-15       Impact factor: 4.379

2.  N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression.

Authors:  Yu-Hsuan Lee; Shih-Bin Su; Chien-Cheng Huang; Hamm-Ming Sheu; Jui-Chen Tsai; Chia-Ho Lin; Ying-Jan Wang; Bour-Jr Wang
Journal:  PLoS One       Date:  2014-09-23       Impact factor: 3.240

  2 in total

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