INTRODUCTION: Although breast reconstruction following mastectomy plays a role in the psychological impact of breast cancer, only one in three women undergo reconstruction. Few multi-institutional studies have compared complication profiles of reconstructive patients to non-reconstructive. METHODS: Using the National Surgical Quality Improvement database, all patients undergoing mastectomy from 2006 to 2010, with or without reconstruction, were identified and risk-stratified using propensity scored quintiles. The incidence of complications and comorbidities were compared. RESULTS: Of 37,723 mastectomies identified, 30% received immediate breast reconstruction. After quintile matching for comorbidities, complications rates between reconstructive and non-reconstructives were similar. This trend was echoed across all quintiles, except in the sub-group with highest comorbidities. Here, the reconstructive patients had significantly more complications than the non-reconstructive (22.8% versus 7.0%, p < 0.001). CONCLUSION: Immediate breast reconstruction is a well-tolerated surgical procedure. However, in patients with high comorbidities, surgeons must carefully counterbalance surgical risks with psychosocial benefits to maximize patient outcomes. LEVEL OF EVIDENCE: Level 3.
INTRODUCTION: Although breast reconstruction following mastectomy plays a role in the psychological impact of breast cancer, only one in three women undergo reconstruction. Few multi-institutional studies have compared complication profiles of reconstructive patients to non-reconstructive. METHODS: Using the National Surgical Quality Improvement database, all patients undergoing mastectomy from 2006 to 2010, with or without reconstruction, were identified and risk-stratified using propensity scored quintiles. The incidence of complications and comorbidities were compared. RESULTS: Of 37,723 mastectomies identified, 30% received immediate breast reconstruction. After quintile matching for comorbidities, complications rates between reconstructive and non-reconstructives were similar. This trend was echoed across all quintiles, except in the sub-group with highest comorbidities. Here, the reconstructive patients had significantly more complications than the non-reconstructive (22.8% versus 7.0%, p < 0.001). CONCLUSION: Immediate breast reconstruction is a well-tolerated surgical procedure. However, in patients with high comorbidities, surgeons must carefully counterbalance surgical risks with psychosocial benefits to maximize patient outcomes. LEVEL OF EVIDENCE: Level 3.
Authors: Indranil Sinha; Andrea L Pusic; Edwin G Wilkins; Jennifer B Hamill; Xiaoxue Chen; Hyungjin M Kim; Gretchen Guldbrandsen; Yoon S Chun Journal: Plast Reconstr Surg Date: 2017-01 Impact factor: 4.730
Authors: Melissa M Sarver; Jess D Rames; Yi Ren; Rachel A Greenup; Ronnie L Shammas; E Shelley Hwang; Scott T Hollenbeck; Terry Hyslop; Paris D Butler; Oluwadamilola M Fayanju Journal: J Am Coll Surg Date: 2022-05-01 Impact factor: 6.532
Authors: Andrea Lisa; Cristina Belgiovine; Luca Maione; Andrea Rimondo; Andrea Battistini; Benedetta Agnelli; Matteo Murolo; Leonardo Galtelli; Marta Monari; Marco Klinger; Valeriano Vinci Journal: Biomed Res Int Date: 2021-03-19 Impact factor: 3.411