Literature DB >> 24351754

Cytotoxic T cell adoptive immunotherapy as a treatment for nasopharyngeal carcinoma.

Viviana P Lutzky1, Pauline Crooks, Leanne Morrison, Natasha Stevens, Joanne E Davis, Monika Corban, David Hall, Benedict Panizza, William B Coman, Scott Coman, Denis J Moss.   

Abstract

Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC). We assess the safety and tolerability of adoptive transfer of autologous cytotoxic T lymphocytes (CTLs) specific for the EBV latent membrane protein (LMP) in a patient with recurrent NPC. After infusion, the majority of pulmonary lesions were no longer evident, although the primary tumor did not regress.

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Year:  2013        PMID: 24351754      PMCID: PMC3910937          DOI: 10.1128/CVI.00121-13

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN: 1556-679X


  18 in total

1.  Epstein-Barr virus-specific cytotoxic T lymphocyte responses in the blood and tumor site of Hodgkin's disease patients: implications for a T-cell-based therapy.

Authors:  A L Chapman; A B Rickinson; W A Thomas; R F Jarrett; J Crocker; S P Lee
Journal:  Cancer Res       Date:  2001-08-15       Impact factor: 12.701

2.  Quantitative analysis of circulating cell-free Epstein-Barr virus (EBV) DNA levels in patients with EBV-associated lymphoid malignancies.

Authors:  K I Lei; L Y Chan; W Y Chan; P J Johnson; Y M Lo
Journal:  Br J Haematol       Date:  2000-10       Impact factor: 6.998

3.  Cell therapy of stage IV nasopharyngeal carcinoma with autologous Epstein-Barr virus-targeted cytotoxic T lymphocytes.

Authors:  Patrizia Comoli; Paolo Pedrazzoli; Rita Maccario; Sabrina Basso; Ornella Carminati; Massimo Labirio; Roberta Schiavo; Simona Secondino; Chiara Frasson; Cesare Perotti; Mauro Moroni; Franco Locatelli; Salvatore Siena
Journal:  J Clin Oncol       Date:  2005-10-03       Impact factor: 44.544

4.  Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease.

Authors:  R Khanna; S Bell; M Sherritt; A Galbraith; S R Burrows; L Rafter; B Clarke; R Slaughter; M C Falk; J Douglass; T Williams; S L Elliott; D J Moss
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

5.  Reconstitution of the latent T-lymphocyte response to Epstein-Barr virus is coincident with long-term recovery from posttransplant lymphoma after adoptive immunotherapy.

Authors:  Martina A Sherritt; Mandvi Bharadwaj; Jacqueline M Burrows; Leanne E Morrison; Suzanne L Elliott; Joanne E Davis; Laurie M Kear; Richard E Slaughter; Scott C Bell; Andrew J Galbraith; Rajiv Khanna; Denis J Moss
Journal:  Transplantation       Date:  2003-05-15       Impact factor: 4.939

Review 6.  Epstein-Barr virus in tumours.

Authors:  I Anagnostopoulos; M Hummel
Journal:  Histopathology       Date:  1996-10       Impact factor: 5.087

7.  Conserved CTL epitopes within EBV latent membrane protein 2: a potential target for CTL-based tumor therapy.

Authors:  S P Lee; R J Tierney; W A Thomas; J M Brooks; A B Rickinson
Journal:  J Immunol       Date:  1997-04-01       Impact factor: 5.422

8.  Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation.

Authors:  C M Rooney; C A Smith; C Y Ng; S Loftin; C Li; R A Krance; M K Brenner; H E Heslop
Journal:  Lancet       Date:  1995-01-07       Impact factor: 79.321

9.  Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes.

Authors:  Karin C M Straathof; Catherine M Bollard; Uday Popat; M Helen Huls; Teresita Lopez; M Craig Morriss; Mary V Gresik; Adrian P Gee; Heidi V Russell; Malcolm K Brenner; Cliona M Rooney; Helen E Heslop
Journal:  Blood       Date:  2004-11-12       Impact factor: 22.113

Review 10.  Cellular responses to viral infection in humans: lessons from Epstein-Barr virus.

Authors:  Andrew D Hislop; Graham S Taylor; Delphine Sauce; Alan B Rickinson
Journal:  Annu Rev Immunol       Date:  2007       Impact factor: 28.527

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  16 in total

1.  Epstein-Barr virus-targeted therapy in nasopharyngeal carcinoma.

Authors:  Sharon D Stoker; Zlata Novalić; Maarten A Wildeman; Alwin D R Huitema; Sandra A W M Verkuijlen; Hedy Juwana; Astrid E Greijer; I Bing Tan; Jaap M Middeldorp; Jan Paul de Boer
Journal:  J Cancer Res Clin Oncol       Date:  2015-04-29       Impact factor: 4.553

Review 2.  Adoptive cellular immunotherapy for virus-associated cancers: a new paradigm in personalized medicine.

Authors:  Corey Smith; Rajiv Khanna
Journal:  Immunol Cell Biol       Date:  2017-01-10       Impact factor: 5.126

3.  Therapeutic vaccine targeting Epstein-Barr virus latent protein, LMP1, suppresses LMP1-expressing tumor growth and metastasis in vivo.

Authors:  Mei-Chun Lin; Yong-Chong Lin; Syue-Ting Chen; Tai-Horng Young; Pei-Jen Lou
Journal:  BMC Cancer       Date:  2017-01-05       Impact factor: 4.430

4.  EBV based cancer prevention and therapy in nasopharyngeal carcinoma.

Authors:  Ya Cao
Journal:  NPJ Precis Oncol       Date:  2017-05-15

Review 5.  Epstein-Barr Virus as a Promising Immunotherapeutic Target for Nasopharyngeal Carcinoma Treatment.

Authors:  Sin-Yeang Teow; Hooi-Yeen Yap; Suat-Cheng Peh
Journal:  J Pathog       Date:  2017-12-31

Review 6.  Annexin A2-mediated cancer progression and therapeutic resistance in nasopharyngeal carcinoma.

Authors:  Chang-Yu Chen; Yung-Song Lin; Chien-Ho Chen; Yin-Ju Chen
Journal:  J Biomed Sci       Date:  2018-03-29       Impact factor: 8.410

7.  Clinical Effect of Adjuvant Cytokine-Induced Killer Cells Immunotherapy in Patients with Stage II-IVB Nasopharyngeal Carcinoma after Chemoradiotherapy: A propensity score analysis.

Authors:  Jing-Jing Zhao; Shu Zhou; Chang-Long Chen; Hong-Xia Zhang; Zi-Qi Zhou; Zheng-Rong Wu; Yuan Liu; Qiu-Zhong Pan; Qian Zhu; Yan Tang; Jian-Chuan Xia; De-Sheng Weng
Journal:  J Cancer       Date:  2018-10-20       Impact factor: 4.207

8.  EBV-Associated Cancer and Autoimmunity: Searching for Therapies.

Authors:  Giovanni Capone; Candida Fasano; Guglielmo Lucchese; Michele Calabrò; Darja Kanduc
Journal:  Vaccines (Basel)       Date:  2015-02-05

Review 9.  Therapeutic implications of Epstein-Barr virus infection for the treatment of nasopharyngeal carcinoma.

Authors:  Susanna Hilda Hutajulu; Johan Kurnianda; I Bing Tan; Jaap M Middeldorp
Journal:  Ther Clin Risk Manag       Date:  2014-09-05       Impact factor: 2.423

10.  Identification of Four-Jointed Box 1 (FJX1)-Specific Peptides for Immunotherapy of Nasopharyngeal Carcinoma.

Authors:  San Jiun Chai; Yoke Yeow Yap; Yoke Ching Foo; Lee Fah Yap; Sathibalan Ponniah; Soo Hwang Teo; Sok Ching Cheong; Vyomesh Patel; Kue Peng Lim
Journal:  PLoS One       Date:  2015-11-04       Impact factor: 3.240

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