| Literature DB >> 24350770 |
Roger Higdon, Elizabeth Stewart, Larissa Stanberry, Winston Haynes, John Choiniere, Elizabeth Montague, Nathaniel Anderson, Gregory Yandl, Imre Janko, William Broomall, Simon Fishilevich, Doron Lancet, Natali Kolker, Eugene Kolker.
Abstract
The Model Organism Protein Expression Database (MOPED, http://moped.proteinspire.org) is an expanding proteomics resource to enable biological and biomedical discoveries. MOPED aggregates simple, standardized and consistently processed summaries of protein expression and metadata from proteomics (mass spectrometry) experiments from human and model organisms (mouse, worm, and yeast). The latest version of MOPED adds new estimates of protein abundance and concentration as well as relative (differential) expression data. MOPED provides a new updated query interface that allows users to explore information by organism, tissue, localization, condition, experiment, or keyword. MOPED supports the Human Proteome Project's efforts to generate chromosome- and diseases-specific proteomes by providing links from proteins to chromosome and disease information as well as many complementary resources. MOPED supports a new omics metadata checklist to harmonize data integration, analysis, and use. MOPED's development is driven by the user community, which spans 90 countries and guides future development that will transform MOPED into a multiomics resource. MOPED encourages users to submit data in a simple format. They can use the metadata checklist to generate a data publication for this submission. As a result, MOPED will provide even greater insights into complex biological processes and systems and enable deeper and more comprehensive biological and biomedical discoveries.Entities:
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Year: 2013 PMID: 24350770 PMCID: PMC4039175 DOI: 10.1021/pr400884c
Source DB: PubMed Journal: J Proteome Res ISSN: 1535-3893 Impact factor: 4.466