Literature DB >> 2435036

Turmeric and curcumin as topical agents in cancer therapy.

R Kuttan, P C Sudheeran, C D Josph.   

Abstract

An ethanol extract of turmeric ("Curcuma longa") as well as an ointment of curcumin (its active ingredient) were found to produce remarkable symptomatic relief in patients with external cancerous lesions. Reduction in smell were noted in 90% of the cases and reduction in itching in almost all cases. Dry lesions were observed in 70% of the cases, and a small number of patients (10%) had a reduction in lesion size and pain. In many patients the effect continued for several months. An adverse reaction was noticed in only one of the 62 patients evaluated.

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Year:  1987        PMID: 2435036     DOI: 10.1177/030089168707300105

Source DB:  PubMed          Journal:  Tumori        ISSN: 0300-8916


  49 in total

Review 1.  Chemopreventive potential of natural compounds in head and neck cancer.

Authors:  Mohammad Aminur Rahman; A R M Ruhul Amin; Dong M Shin
Journal:  Nutr Cancer       Date:  2010       Impact factor: 2.900

Review 2.  Cancer cell signaling pathways targeted by spice-derived nutraceuticals.

Authors:  Bokyung Sung; Sahdeo Prasad; Vivek R Yadav; Bharat B Aggarwal
Journal:  Nutr Cancer       Date:  2011-12-09       Impact factor: 2.900

3.  Epigenetic changes induced by curcumin and other natural compounds.

Authors:  Simone Reuter; Subash C Gupta; Byoungduck Park; Ajay Goel; Bharat B Aggarwal
Journal:  Genes Nutr       Date:  2011-04-24       Impact factor: 5.523

Review 4.  Perspectives for cancer prevention with natural compounds.

Authors:  A R M Ruhul Amin; Omer Kucuk; Fadlo R Khuri; Dong M Shin
Journal:  J Clin Oncol       Date:  2009-05-04       Impact factor: 44.544

Review 5.  Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases.

Authors:  Ajaikumar B Kunnumakkara; Devivasha Bordoloi; Ganesan Padmavathi; Javadi Monisha; Nand Kishor Roy; Sahdeo Prasad; Bharat B Aggarwal
Journal:  Br J Pharmacol       Date:  2016-10-21       Impact factor: 8.739

Review 6.  Therapeutic roles of curcumin: lessons learned from clinical trials.

Authors:  Subash C Gupta; Sridevi Patchva; Bharat B Aggarwal
Journal:  AAPS J       Date:  2012-11-10       Impact factor: 4.009

Review 7.  Hitting the golden TORget: curcumin's effects on mTOR signaling.

Authors:  Christopher S Beevers; Hongyu Zhou; Shile Huang
Journal:  Anticancer Agents Med Chem       Date:  2013-09       Impact factor: 2.505

8.  Topical application of a sandal wood oil and turmeric based cream prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy: a pilot study.

Authors:  P L Palatty; A Azmidah; S Rao; D Jayachander; K R Thilakchand; M P Rai; R Haniadka; P Simon; R Ravi; R Jimmy; P F D'souza; R Fayad; M S Baliga
Journal:  Br J Radiol       Date:  2014-04-02       Impact factor: 3.039

Review 9.  Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways.

Authors:  Satya Narayan
Journal:  J Mol Histol       Date:  2004-03       Impact factor: 2.611

Review 10.  Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers.

Authors:  Bharat B Aggarwal; Subash C Gupta; Bokyung Sung
Journal:  Br J Pharmacol       Date:  2013-08       Impact factor: 8.739

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