Literature DB >> 24349877

RELATIONSHIP OF GAIT AND COGNITION IN THE ELDERLY.

Raminder Parihar1, Jeannette R Mahoney1, Joe Verghese2.   

Abstract

Gait and cognitive impairments in older adults mostly reflect the co-occurrence of two geriatric syndromes linked by common underlying brain substrates and pathologies. Gait control is predominately mediated by frontal subcortical circuits, which overlap with circuits controlling executive control and attention functions. These circuits are vulnerable to multiple age-related pathologies such as ischemia, inflammation, and neurodegeneration, which could ultimately cause cognitive, gait, or combined cognitive and gait impairments. The following review aims to describe various gait and cognitive classifications, gait based phenotypes, common underlying pathological processes, and provide a link between motor and cognitive impairments in an effort to predict the risk of dementia, as well as remediate impairments by applying appropriate interventions.

Entities:  

Keywords:  Gait; cognition; dementia risk; dual-task; gait phenotypes; inflammation; neurodegeneration; quantitative gait measurements; remediation; vascular

Year:  2013        PMID： 24349877      PMCID： PMC3859437          DOI： 10.1007/s13670-013-0052-7

Source DB:  PubMed          Journal:  Curr Transl Geriatr Exp Gerontol Rep        ISSN： 2162-4941


  75 in total

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Journal:  Adv Neurol       Date:  2001

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Authors:  Gilles Kemoun; Marie Thibaud; Nicolas Roumagne; Pierre Carette; Cédric Albinet; Lucette Toussaint; Marc Paccalin; Benoit Dugué
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5.  Neurological gait abnormalities and risk of falls in older adults.

Authors:  Joe Verghese; Anne F Ambrose; Richard B Lipton; Cuiling Wang
Journal:  J Neurol       Date:  2009-09-26       Impact factor: 4.849

Review 6.  Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force.

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Journal:  J Nutr Health Aging       Date:  2009-12       Impact factor: 4.075

7.  Mobility stress test approach to predicting frailty, disability, and mortality in high-functioning older adults.

Authors:  Joe Verghese; Roee Holtzer; Richard B Lipton; Cuiling Wang
Journal:  J Am Geriatr Soc       Date:  2012-09-24       Impact factor: 5.562

8.  Physiological factors associated with falls in older community-dwelling women.

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Journal:  J Am Geriatr Soc       Date:  1994-10       Impact factor: 5.562

9.  Motoric cognitive risk syndrome and the risk of dementia.

Authors:  Joe Verghese; Cuiling Wang; Richard B Lipton; Roee Holtzer
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2012-09-17       Impact factor: 6.053

10.  Total mortality after changes in leisure time physical activity in 50 year old men: 35 year follow-up of population based cohort.

Authors:  Liisa Byberg; Håkan Melhus; Rolf Gedeborg; Johan Sundström; Anders Ahlbom; Björn Zethelius; Lars G Berglund; Alicja Wolk; Karl Michaëlsson
Journal:  BMJ       Date:  2009-03-05
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  19 in total

1.  Brain health: the importance of recognizing cognitive impairment: an IAGG consensus conference.

Authors:  John E Morley; John C Morris; Marla Berg-Weger; Soo Borson; Brian D Carpenter; Natalia Del Campo; Bruno Dubois; Keith Fargo; L Jaime Fitten; Joseph H Flaherty; Mary Ganguli; George T Grossberg; Theodore K Malmstrom; Ronald D Petersen; Carroll Rodriguez; Andrew J Saykin; Philip Scheltens; Eric G Tangalos; Joe Verghese; Gordon Wilcock; Bengt Winblad; Jean Woo; Bruno Vellas
Journal:  J Am Med Dir Assoc       Date:  2015-09-01       Impact factor: 4.669

2.  Ramadan Fasting Effects on Postural Control in the Elderly: A Comparison Between Fallers and Non-fallers.

Authors:  Rabeb Laatar; Rym Baccouch; Rihab Borji; Hiba Kachouri; Haithem Rebai; Sonia Sahli
Journal:  J Relig Health       Date:  2019-02

3.  Dual task interference on postural sway, postural transitions and gait in people with Parkinson's disease and freezing of gait.

Authors:  Ana Claudia de Souza Fortaleza; Martina Mancini; Patty Carlson-Kuhta; Laurie A King; John G Nutt; Eliane Ferrari Chagas; Ismael Forte Freitas; Fay B Horak
Journal:  Gait Posture       Date:  2017-05-10       Impact factor: 2.840

4.  Activity engagement and physical function in old age sample.

Authors:  Krupa N Shah; Feng V Lin; Fang Yu; James M McMahon
Journal:  Arch Gerontol Geriatr       Date:  2016-11-17       Impact factor: 3.250

5.  Relations of Executive Function and Physical Performance in Middle Adulthood: A Prospective Investigation in African American and White Adults.

Authors:  Daniel K Leibel; Megan R Williams; Leslie I Katzel; Michele K Evans; Alan B Zonderman; Shari R Waldstein
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2020-06-02       Impact factor: 4.077

Review 6.  Driving Performance in Older Adults: Current Measures, Findings, and Implications for Roadway Safety.

Authors:  Robert Toups; Theresa J Chirles; Johnathon P Ehsani; Jeffrey P Michael; John P K Bernstein; Matthew Calamia; Thomas D Parsons; David B Carr; Jeffrey N Keller
Journal:  Innov Aging       Date:  2022-01-07

7.  Cognitive Motor Dual Task Costs in Older Adults with Motoric Cognitive Risk Syndrome.

Authors:  N Ward; A Menta; S Peach; S A White; S Jaffe; C Kowaleski; K Grandjean da Costa; J Verghese; K F Reid
Journal:  J Frailty Aging       Date:  2021

Review 8.  Gait dyspraxia as a clinical marker of cognitive decline in Down syndrome: A review of theory and proposed mechanisms.

Authors:  Amelia J Anderson-Mooney; Frederick A Schmitt; Elizabeth Head; Ira T Lott; Kenneth M Heilman
Journal:  Brain Cogn       Date:  2016-02-27       Impact factor: 2.310

9.  Metabolic Syndrome and Physical Performance: The Moderating Role of Cognition among Middle-to-Older-Aged Adults.

Authors:  Elisa F Ogawa; Elizabeth Leritz; Regina McGlinchey; William Milberg; Jonathan F Bean
Journal:  J Int Neuropsychol Soc       Date:  2020-08-10       Impact factor: 2.892

10.  Integrating Frailty and Cognitive Phenotypes: Why, How, Now What?

Authors:  Qian-Li Xue; Brian Buta; Lina Ma; Meiling Ge; Michelle Carlson
Journal:  Curr Geriatr Rep       Date:  2019-04-24
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