| Literature DB >> 24347375 |
Li Zhou1, Zhaowei Chen, Kai Dong, Meili Yin, Jinsong Ren, Xiaogang Qu.
Abstract
A simple DNA-mediated solvothermal method has been developed for the construction of well-defined hollow UNPs that can be used for a new paradigm to realize NIR light-controlled non-invasive protein release. In vitro studies show that the UNPs are capable of the transportation of enzyme into living cells. Intracellular NIR triggers the release of enzymes with high spatial and temporal precision and the released enzyme also retains its biological activity.Keywords: DNA; hollow particles; nanoparticles; near-infrared light; protein delivery; solvothermal method; upconversion
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Year: 2013 PMID: 24347375 DOI: 10.1002/adma.201304437
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849