Literature DB >> 2434676

Effects of pH on the Na-Ca exchange current in single ventricular cells of the guinea pig.

Y E Earm, H Irisawa.   

Abstract

Using isolated guinea pig single ventricular cell, the sodium-calcium exchange current was recorded. Both internal and external acidification to pH 6 abolished most of the sodium-calcium exchange current and alkalinization to pH 8 decreased the exchange current. Thus, pH change modulates Na-Ca exchange current both from inside and outside of the cell.

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Year:  1986        PMID： 2434676

Source DB:  PubMed          Journal:  Jpn Heart J        ISSN： 0021-4868


  5 in total

1.  Cardiac pacemaker cell failure with preserved I(f), I(CaL), and I(Kr): a lesson about pacemaker function learned from ischemia-induced bradycardia.

Authors:  Victor A Maltsev; Edward G Lakatta
Journal:  J Mol Cell Cardiol       Date:  2006-12-22       Impact factor: 5.000

2.  Changes in myoplasmic pH and calcium concentration during exposure to lactate in isolated rat ventricular myocytes.

Authors:  S P Cairns; H Westerblad; D G Allen
Journal:  J Physiol       Date:  1993-05       Impact factor: 5.182

3.  Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide.

Authors:  Michiel ten Hove; Jan G van Emous; Cees J A van Echteld
Journal:  Mol Cell Biochem       Date:  2003-08       Impact factor: 3.396

4.  The mechanism by which cytoplasmic protons inhibit the sodium-calcium exchanger in guinea-pig heart cells.

Authors:  A E Doering; W J Lederer
Journal:  J Physiol       Date:  1993-07       Impact factor: 5.182

5.  Effects of acidosis on ventricular myocyte shortening and intracellular Ca2+ in streptozotocin-induced diabetic rats.

Authors:  Frank Christopher Howarth; Anwar Qureshi; Jaipaul Singh
Journal:  Mol Cell Biochem       Date:  2004-06       Impact factor: 3.396
  5 in total

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