Literature DB >> 24346112

Noninvasive measurements of hemodynamic transition directly after birth.

Jeroen J van Vonderen1, Arno A W Roest2, Melissa L Siew3, Nico A Blom2, Jan M van Lith4, Frans J Walther1, Stuart B Hooper3, Arjan B te Pas1.   

Abstract

BACKGROUND: Cardiac output depends on stroke volume and heart rate (HR). Only HR is used to monitor hemodynamic transition.
METHODS: In 24 term newborns born via cesarean section, HR and preductal blood pressure (BP) were measured. Also, using echocardiography, left ventricular dimensions and (Doppler derived) left ventricular output (LVO) were examined at 2, 5, and 10 min after birth.
RESULTS: Mean (SD) HR and BP did not change with time (mean HR: 157 (21) bpm at 2 min, 154 (17) bpm at 5 min, and 155 (14) bpm at 10 min; mean BP: 51.2 (15.4) mm Hg at 2 min, 50.5 (11.7) mm Hg at 5 min, and 49.6 (9.5) mm Hg at 10 min). Left ventricular end-diastolic diameter increased from 2 to 5 min (14.3 (1.3) vs. 16.3 (1.7) mm; P < 0.001) and stabilized at 10 min (16.7 (1.4) mm). LVO increased between 2 and 5 min (151 (47) vs. 203 (55) ml/kg/min; P < 0.001) and stabilized at 10 min (201 (45) ml/kg/min). LVO increase was associated with rise in left ventricular stroke volume (r = 0.94; P < 0.001), not with rise in HR (r = 0.37; P value not significant).
CONCLUSION: Left ventricular dimensions and LVO significantly increased the first 5 min after birth and stabilized at 10 min, whereas BP remained stable. LVO and left ventricular dimension increase are presumably due to increasing left ventricular preload resulting from pulmonary blood flow and ductal shunting increase.

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Year:  2013        PMID: 24346112     DOI: 10.1038/pr.2013.241

Source DB:  PubMed          Journal:  Pediatr Res        ISSN: 0031-3998            Impact factor:   3.756


  20 in total

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8.  Cardiac Output and Cerebral Oxygenation in Term Neonates during Neonatal Transition.

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Review 9.  Cardiorespiratory Monitoring during Neonatal Resuscitation for Direct Feedback and Audit.

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Review 10.  Enhanced Monitoring of the Preterm Infant during Stabilization in the Delivery Room.

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