OBJECTIVES: The aim of this study was to evaluate the effect of an intensive physical therapy protocol in patients who contract 'intensive care unit-acquired weakness' (ICUAW), in terms of muscle strength, breathing and functional indices. METHODS: This was a prospective, single-blinded study in a general hospital intensive care unit (ICU). Patients who required mechanical ventilation longer than 48 h and who were expected to remain mechanically ventilated for at least another 48 h were randomly divided into two intervention groups: group I (n = 9) - the routine care group, received physical therapy according to our daily custom protocol; and group II (n = 9) - the intensive treatment group, were treated by the same protocol twice a day. The main outcome measures included the Medical Research Council (MRC) physical strength examination, maximal inspiratory pressure (MIP), hand grip dynamometer and sitting balance test. RESULTS: Significant strength improvement from first (T1) to second (T2) measurements was demonstrated for variables MIP and MRC physical strength examination in favor of the intensive treatment group (P < 0.05). The intensive treatment group also required shorter intensive care length of stay than the routine care group (P = 0.043). CONCLUSIONS: It is possible that an intensive therapy protocol may facilitate the initial recovery process in patients who suffer from ICUAW.
RCT Entities:
OBJECTIVES: The aim of this study was to evaluate the effect of an intensive physical therapy protocol in patients who contract 'intensive care unit-acquired weakness' (ICUAW), in terms of muscle strength, breathing and functional indices. METHODS: This was a prospective, single-blinded study in a general hospital intensive care unit (ICU). Patients who required mechanical ventilation longer than 48 h and who were expected to remain mechanically ventilated for at least another 48 h were randomly divided into two intervention groups: group I (n = 9) - the routine care group, received physical therapy according to our daily custom protocol; and group II (n = 9) - the intensive treatment group, were treated by the same protocol twice a day. The main outcome measures included the Medical Research Council (MRC) physical strength examination, maximal inspiratory pressure (MIP), hand grip dynamometer and sitting balance test. RESULTS: Significant strength improvement from first (T1) to second (T2) measurements was demonstrated for variables MIP and MRC physical strength examination in favor of the intensive treatment group (P < 0.05). The intensive treatment group also required shorter intensive care length of stay than the routine care group (P = 0.043). CONCLUSIONS: It is possible that an intensive therapy protocol may facilitate the initial recovery process in patients who suffer from ICUAW.
Authors: Selina M Parry; Catherine L Granger; Sue Berney; Jennifer Jones; Lisa Beach; Doa El-Ansary; René Koopman; Linda Denehy Journal: Intensive Care Med Date: 2015-02-05 Impact factor: 17.440
Authors: Claire J Tipping; Meg Harrold; Anne Holland; Lorena Romero; Travis Nisbet; Carol L Hodgson Journal: Intensive Care Med Date: 2016-11-18 Impact factor: 17.440
Authors: Stefannie Vorona; Umberto Sabatini; Sulaiman Al-Maqbali; Michele Bertoni; Martin Dres; Bernie Bissett; Frank Van Haren; A Daniel Martin; Cristian Urrea; Debbie Brace; Matteo Parotto; Margaret S Herridge; Neill K J Adhikari; Eddy Fan; Luana T Melo; W Darlene Reid; Laurent J Brochard; Niall D Ferguson; Ewan C Goligher Journal: Ann Am Thorac Soc Date: 2018-06
Authors: Guo-Wei Tu; Jie-Qiong Song; Simon Kang Seng Ting; Min-Jie Ju; Hong-Yu He; Ji-Hong Dong; Zhe Luo Journal: Eur J Med Res Date: 2015-02-03 Impact factor: 2.175
Authors: Pedro Verissimo; Thaisa Juliana André Casalaspo; Louise Helena Rodrigues Gonçalves; Angela Shu Yun Yang; Raquel Caserta Eid; Karina T Timenetsky Journal: PLoS One Date: 2015-02-11 Impact factor: 3.240