Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Regenerative medicine: transdifferentiation in vivo.

Literature DB >> 24343579

Regenerative medicine: transdifferentiation in vivo.

Lina Fu¹, Xiping Zhu¹, Fei Yi², Guang-Hui Liu³, Juan Carlos Izpisua Belmonte⁴.

Abstract

A major challenge in regenerative medicine is the generation of functionally effective target cells to replace or repair damaged tissues. Transdifferentiation in vivo is a novel strategy to achieve cell fate conversion within the native physiological niche; this technology may provide a time- and cost-effective alternative for applications in regenerative medicine and may also minimize the concerns associated with in vitro culture and cell transplantation.

Mesh：

Substances：
Transcription Factors

Year: 2013 PMID： 24343579 PMCID： PMC3915906 DOI： 10.1038/cr.2013.165

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

10 in total

1. Reprogramming in vivo produces teratomas and iPS cells with totipotency features.

Authors: María Abad; Lluc Mosteiro; Cristina Pantoja; Marta Cañamero; Teresa Rayon; Inmaculada Ors; Osvaldo Graña; Diego Megías; Orlando Domínguez; Dolores Martínez; Miguel Manzanares; Sagrario Ortega; Manuel Serrano
Journal: Nature Date: 2013-09-11 Impact factor: 49.962

2. In vivo reprogramming of astrocytes to neuroblasts in the adult brain.

Authors: Wenze Niu; Tong Zang; Yuhua Zou; Sanhua Fang; Derek K Smith; Robert Bachoo; Chun-Li Zhang
Journal: Nat Cell Biol Date: 2013-09-22 Impact factor: 28.824

3. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.

Authors: Masaki Ieda; Ji-Dong Fu; Paul Delgado-Olguin; Vasanth Vedantham; Yohei Hayashi; Benoit G Bruneau; Deepak Srivastava
Journal: Cell Date: 2010-08-06 Impact factor: 41.582

4. Generation of induced neurons via direct conversion in vivo.

Authors: Olof Torper; Ulrich Pfisterer; Daniel A Wolf; Maria Pereira; Shong Lau; Johan Jakobsson; Anders Björklund; Shane Grealish; Malin Parmar
Journal: Proc Natl Acad Sci U S A Date: 2013-03-25 Impact factor: 11.205

5. Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo.

Authors: Caroline Rouaux; Paola Arlotta
Journal: Nat Cell Biol Date: 2013-01-20 Impact factor: 28.824

6. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors: Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal: Cell Date: 2007-11-30 Impact factor: 41.582

7. In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts.

Authors: Anannya Banga; Ersin Akinci; Lucas V Greder; James R Dutton; Jonathan M W Slack
Journal: Proc Natl Acad Sci U S A Date: 2012-09-04 Impact factor: 11.205

8. Heart repair by reprogramming non-myocytes with cardiac transcription factors.

Authors: Kunhua Song; Young-Jae Nam; Xiang Luo; Xiaoxia Qi; Wei Tan; Guo N Huang; Asha Acharya; Christopher L Smith; Michelle D Tallquist; Eric G Neilson; Joseph A Hill; Rhonda Bassel-Duby; Eric N Olson
Journal: Nature Date: 2012-05-13 Impact factor: 49.962

9. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.

Authors: Li Qian; Yu Huang; C Ian Spencer; Amy Foley; Vasanth Vedantham; Lei Liu; Simon J Conway; Ji-dong Fu; Deepak Srivastava
Journal: Nature Date: 2012-05-31 Impact factor: 49.962

10. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.

Authors: Qiao Zhou; Juliana Brown; Andrew Kanarek; Jayaraj Rajagopal; Douglas A Melton
Journal: Nature Date: 2008-08-27 Impact factor: 49.962

10 in total

11 in total

1. Expanding horizons of cellular plasticity in regenerative medicine.

Authors: Chandan K Sen
Journal: Am J Pathol Date: 2015-10 Impact factor: 4.307

Review 2. Forward engineering neuronal diversity using direct reprogramming.

Authors: Rachel K Tsunemoto; Kevin T Eade; Joel W Blanchard; Kristin K Baldwin
Journal: EMBO J Date: 2015-04-23 Impact factor: 11.598

Review 3. Generation of diverse neural cell types through direct conversion.

Authors: Gayle F Petersen; Padraig M Strappe
Journal: World J Stem Cells Date: 2016-02-26 Impact factor: 5.326

4. Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice.

Authors: Charleen Hunt; Suzanne A Hartford; Derek White; Evangelos Pefanis; Timothy Hanna; Clarissa Herman; Jarrell Wiley; Heather Brown; Qi Su; Yurong Xin; Dennis Voronin; Hien Nguyen; Judith Altarejos; Keith Crosby; Jeffery Haines; Sarah Cancelarich; Meghan Drummond; Sven Moller-Tank; Ryan Malpass; Jacqueline Buckley; Maria Del Pilar Molina-Portela; Gustavo Droguett; David Frendewey; Eric Chiao; Brian Zambrowicz; Guochun Gong
Journal: Nat Commun Date: 2021-05-13 Impact factor: 14.919

5. Regeneration of the digestive system in the crinoid Himerometra robustipinna occurs by transdifferentiation of neurosecretory-like cells.

Authors: Nadezhda V Kalacheva; Marina G Eliseikina; Lidia T Frolova; Igor Yu Dolmatov
Journal: PLoS One Date: 2017-07-28 Impact factor: 3.240

6. Thrombus leukocytes exhibit more endothelial cell-specific angiogenic markers than peripheral blood leukocytes do in acute coronary syndrome patients, suggesting a possibility of trans-differentiation: a comprehensive database mining study.

Authors: Hangfei Fu; Nish Vadalia; Eric R Xue; Candice Johnson; Luqiao Wang; William Y Yang; Claudette Sanchez; Jun Nelson; Qian Chen; Eric T Choi; Jian-Xing Ma; Jun Yu; Hong Wang; Xiaofeng Yang
Journal: J Hematol Oncol Date: 2017-03-23 Impact factor: 17.388