Literature DB >> 24343195

Co-delivery of small interfering RNA using a camptothecin prodrug as the carrier.

Qiong Tang1, Bin Cao, Gang Cheng.   

Abstract

We have reported the first effort towards directly using an anticancer prodrug (CPTssR5H5) as a carrier to co-deliver camptothecin (CPT) and small interfering RNA for multidrug resistant cancer chemotherapy. The results indicated that CPTssR5H5 is a promising co-delivery system for MDR cancer therapy.

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Year:  2014        PMID： 24343195     DOI： 10.1039/c3cc47970f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

Review 1.  Novel delivery approaches for cancer therapeutics.

Authors:  Ashim K Mitra; Vibhuti Agrahari; Abhirup Mandal; Kishore Cholkar; Chandramouli Natarajan; Sujay Shah; Mary Joseph; Hoang M Trinh; Ravi Vaishya; Xiaoyan Yang; Yi Hao; Varun Khurana; Dhananjay Pal
Journal:  J Control Release       Date:  2015-10-09       Impact factor: 9.776

2.  Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing.

Authors:  Manon Ripoll; Marie Pierdant; Patrick Neuberg; Dominique Bagnard; Alain Wagner; Antoine Kichler; Jean-Serge Remy
Journal:  RSC Adv       Date:  2018-06-06       Impact factor: 3.361

3.  Multistage rocket: integrational design of a prodrug-based siRNA delivery system with sequential release for enhanced antitumor efficacy.

Authors:  Qian Jiang; Xiaobing Chen; Hong Liang; Yu Nie; Rongrong Jin; Matthias Barz; Dong Yue; Zhongwei Gu
Journal:  Nanoscale Adv       Date:  2018-10-20
  3 in total

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