| Literature DB >> 24342801 |
Enagnon Kazali Alidjinou1, Donatien Moukassa2, Famara Sané1, Séraphin Twagirimana Nyenyeli2, Estina Chandrelle Akoko2, Michèle Valy Mountou2, Laurence Bocket1, Jean-Rosaire Ibara3, Didier Hober4.
Abstract
The detection of hepatitis B virus (HBV) infection markers by using dried plasma spots from 32 patients living in Congo has been assessed. Considering frozen plasma samples as gold standard, the sensitivity and specificity of HBV serologic markers detection in dried plasma eluted from filter paper were 100%. The sensitivity and the specificity of HBV DNA detection reached 96% and 100%, respectively, with plasma samples dried on filter paper compared to standard samples. Dried plasma samples can represent an alternative to conventional sampling for HBV detection and management of the infection in developing countries.Entities:
Keywords: Congo-Brazzaville; Dried plasma spots; HBV DNA; HBV antibodies; HBV antigens
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Year: 2013 PMID: 24342801 DOI: 10.1016/j.diagmicrobio.2013.09.019
Source DB: PubMed Journal: Diagn Microbiol Infect Dis ISSN: 0732-8893 Impact factor: 2.803